Functionalization of Synthetic Bone Substitutes

Bone substitutes have been applied to treat osseous defects for a long time. To prevent implant related infection (IRI) and enhance bone healing functionalized biomaterials, antibiotics and osteoinductive substances have been introduced. This study gives an overview of the current available surface-coated bone substitutes and provides an outlook for future perspectives.

Automated summary

Bone substitutes have long been used to treat osseous defects. In order to prevent implant-related infection and enhance bone healing, functionalized biomaterials, antibiotics, and osteoinductive substances have been introduced. This study provides an overview of current surface-coated bone substitutes and offers insights into future perspectives.