期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 22, 期 7, 页码 -出版社
MDPI
DOI: 10.3390/ijms22073587
关键词
cytokines; immune cells; markers; multiple myeloma; prognostic factors
资金
- Polish National Science Center [UMO-2016/21/B/NZ6/02279]
- Medical University of Lublin [DS460, DS461]
The article discusses the prognostic value of immune system components in patients with multiple myeloma to aid in the development of new diagnostic and therapeutic directions.
Multiple myeloma (MM) is a plasma cell neoplasm characterized by an abnormal proliferation of clonal, terminally differentiated B lymphocytes. Current approaches for the treatment of MM focus on developing new diagnostic techniques; however, the search for prognostic markers is also crucial. This enables the classification of patients into risk groups and, thus, the selection of the most optimal treatment method. Particular attention should be paid to the possible use of immune factors, as the immune system plays a key role in the formation and course of MM. In this review, we focus on characterizing the components of the immune system that are of prognostic value in MM patients, in order to facilitate the development of new diagnostic and therapeutic directions.
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