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Bilal R. Malik et al.
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Peidu Jiang et al.
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Marta Moskot et al.
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Seiya Ishibashi et al.
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A. Schmidt et al.
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Ewa Piotrowska et al.
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Guanghong Liao et al.
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Christopher D. Pacheco et al.
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Ina N. Talke et al.
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EP Beltroy et al.
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TH Tsai
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C Ramakers et al.
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