The Role of Innate and Adaptive Immune Cells in Skeletal Muscle Regeneration

Skeletal muscle regeneration is highly dependent on the inflammatory response. A wide variety of innate and adaptive immune cells orchestrate the complex process of muscle repair. This review provides information about the various types of immune cells and biomolecules that have been shown to mediate muscle regeneration following injury and degenerative diseases. Recently developed cell and drug-based immunomodulatory strategies are highlighted. An improved understanding of the immune response to injured and diseased skeletal muscle will be essential for the development of therapeutic strategies.

Automated summary

The inflammatory response plays a critical role in skeletal muscle regeneration, with various immune cells and biomolecules involved in the process of muscle repair. Research has focused on utilizing immune cells and biomolecules to promote muscle regeneration, along with the development of cell and drug-based immunomodulatory strategies.