期刊
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
卷 108, 期 -, 页码 212-216出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.ijid.2021.04.063
关键词
SARS-CoV-2; SARS-CoV-2 aerosols; SARS-CoV-2 in vehicles
资金
- University of Florida Emerging Pathogens Institute
The study found that minimally symptomatic individuals can potentially transmit SARS-CoV-2 via aerosolized virus in the closed space inside a car, highlighting an increased risk of virus transmission in such environments.
Objective: To determine if viable virus could be isolated from the air within a car driven by a patient infected with SARS-CoV-2, and to assess the size range of the infectious particles. Methods: We used a Sioutas personal cascade impactor sampler (PCIS) to screen for SARS-CoV-2 in a car driven by a COVID-19 patient. The patient, who had only mild illness without fever or cough and was not wearing a mask, drove the car for 15 min with the air conditioning turned on and windows closed. The PCIS was clipped to the sun-visor above the front passenger seat and was retrieved from the car two hours after completion of the drive. Results: SARS-CoV-2 was detectable at all PCIS stages by PCR and was cultured from the section of the sampler collecting particles in the 0.25-0.50 mm size range. Conclusions: Our data highlight the potential risk of SARS-CoV-2 transmission by minimally symptomatic persons in the closed space inside of a car and suggest that a substantial component of that risk is via aerosolized virus. (C) 2021 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.
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