The role of interleukin-10 family members in cardiovascular diseases

Interleukin (IL)-10 cytokine family members, including IL-10, IL-19, IL-20, IL-22, IL-24, IL-26 and the distantly related IL-28A, IL-28B, and IL-29, play critical roles in the regulation of inflammation. The occurrence and progression of cardiovascular diseases closely correlate with the regulation of inflammation, which may provide novel strategies for the treatment of cardiovascular diseases. In recent years, studies have focused on the association between the IL-10 cytokine family and the physiological and pathological progression of cardiovascular diseases. The aim of this review is to summarize relevant studies and clarify whether the IL-10 cytokine family contributes to the regulation of cardiovascular diseases.

Automated summary

Members of the IL-10 cytokine family, such as IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28A, IL-28B, and IL-29, play critical roles in regulating inflammation, which is closely associated with the occurrence and progression of cardiovascular diseases. Studies have focused on the relationship between the IL-10 cytokine family and cardiovascular diseases, aiming to determine their contribution to disease regulation.