4.3 Article

Stable spike clusters for the one-dimensional Gierer-Meinhardt system

期刊

EUROPEAN JOURNAL OF APPLIED MATHEMATICS
卷 28, 期 4, 页码 576-635

出版社

CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0956792516000450

关键词

35B35; 35J75; 35K57; 35K58; 92C15

资金

  1. NSERC of Canada
  2. EPSRC [EP/K032208/1]

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We consider the Gierer-Meinhardt system with precursor inhomogeneity and two small diffusivities in an interval {A(t) = epsilon(2) A '' - mu(x) A + A(2)/H, x is an element of(- 1, 1), t > 0, tau H-t = DH '' - H + A(2), x is an element of(- 1, 1), t > 0, A' (- 1) = A' (1) = H' (-1) = H' (1) = 0, where 0 < epsilon << root D << 1, tau >= 0 and tau is independent of epsilon. A spike cluster is the combination of several spikes which all approach the same point in the singular limit. We rigorously prove the existence of a steady-state spike cluster consisting of N spikes near a non-degenerate local minimum point t(0) of the smooth positive inhomogeneity mu(x), i.e. we assume that mu'(t(0)) = 0, mu ''(t(0)) > 0 and we have mu(t(0)) > 0. Here, N is an arbitrary positive integer. Further, we show that this solution is linearly stable. We explicitly compute all eigenvalues, both large (of order O(1)) and small (of order o(1)). The main features of studying the Gierer-Meinhardt system in this setting are as follows: (i) it is biologically relevant since it models a hierarchical process (pattern formation of small-scale structures induced by a pre-existing large-scale inhomogeneity); (ii) it contains three different spatial scales two of which are small: the O(1) scale of the precursor inhomogeneity mu(x), the O(root D) scale of the inhibitor diffusivity and the O(epsilon) scale of the activator diffusivity; (iii) the expressions can be made explicit and often have a particularly simple form.

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