期刊
IEEE TRANSACTIONS ON CIRCUITS AND SYSTEMS II-EXPRESS BRIEFS
卷 68, 期 5, 页码 1735-1739出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TCSII.2021.3066556
关键词
Neural-recording; multi-channel; frequency division multiplexing (FDM); graphene
资金
- National Institutes of Health through the NIH BRAIN Initiative [R21EY030007]
The research proposes a method to break the traditional N-wire, N-electrode array architecture using graphene active electrodes and frequency-division multiplexing. This approach can increase signal count, spatial resolution, and temporal precision while decreasing access wires.
Multielectrode arrays are used broadly for neural recording, both in vivo and for ex vivo cultured neurons. In most cases, recording sites are passive electrodes wired to external read-out circuitry, and the number of wires is at least equal to the number of recording sites. We present an approach to break the conventional N-wire, N-electrode array architecture using graphene active electrodes, which allow signal upconversion at the recording site and sharing of each interface wire among multiple active electrodes using frequency-division multiplexing (FDM). The presented work includes the design and implementation of a frequency modulation and readout architecture using graphene FET electrodes, a custom integrated circuit (IC) analog front-end (AFE), and digital demodulation. The AFE was fabricated in 0.18 mu m CMOS; electrical characterization and multi-channel FDM results are provided, including GFET-based signal modulation and IC/DSP demodulation. Long-term, this approach can simultaneously enable high signal count, high spatial resolution, and high temporal precision to infer functional interactions between neurons while markedly decreasing access wires.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据