期刊
HYPERTENSION IN PREGNANCY
卷 40, 期 3, 页码 180-185出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/10641955.2021.1921792
关键词
Meta-analysis; multiple sclerosis; preeclampsia; systematic review
Through systematic review and meta-analysis, it was found that multiple sclerosis is not associated with the risk of preeclampsia.
Objective: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE). Methods: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The I-2 measured heterogeneity between studies. Results: Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI: 0.89, 1.09; I-2 = 0.00%). Conclusion: MS is not associated with PE.
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