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Francois Dossin et al.
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Molecular signatures of X chromosome inactivation and associations with clinical outcomes in epithelial ovarian cancer
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Loss of SETDB1 decompacts the inactive X chromosome in part through reactivation of an enhancer in the IL1RAPL1 gene
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PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation
Mafalda Almeida et al.
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X-chromosome inactivation in female patients with Fabry disease
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Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture
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Unusual maintenance of X chromosome inactivation predisposes female lymphocytes for increased expression from the inactive X
Jianle Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing
Andrew Keniry et al.
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Systematic Discovery of Xist RNA Binding Proteins
Ci Chu et al.
CELL (2015)
The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer
Ronan Chaligne et al.
GENOME RESEARCH (2015)
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3
Colleen A. McHugh et al.
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Dysregulation of X Chromosome Inactivation in High Grade Ovarian Serous Adenocarcinoma
Jun Kang et al.
PLOS ONE (2015)
A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing
Benoit Moindrot et al.
CELL REPORTS (2015)
Identification of Spen as a Crucial Factor for Xist Function through Forward Genetic Screening in Haploid Embryonic Stem Cells
Asun Monfort et al.
CELL REPORTS (2015)
Landscape of DNA methylation on the X chromosome reflects CpG density, functional chromatin state and X-chromosome inactivation
Allison M. Cotton et al.
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ATRX Directs Binding of PRC2 to Xist RNA and Polycomb Targets
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N-terminal phosphorylation of HP1α increases its nucleosome-binding specificity
Gohei Nishibuchi et al.
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The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation
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A prominent and conserved role for YY1 in Xist transcriptional activation
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NATURE COMMUNICATIONS (2014)
Jpx RNA Activates Xist by Evicting CTCF
Sha Sun et al.
CELL (2013)
High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation
Matthew D. Simon et al.
NATURE (2013)
Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway
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RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3
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Smchd1-Dependent and -Independent Pathways Determine Developmental Dynamics of CpG Island Methylation on the Inactive X Chromosome
Anne-Valerie Gendrel et al.
DEVELOPMENTAL CELL (2012)
Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations
Stefan F. Pinter et al.
GENOME RESEARCH (2012)
The macrosatellite DXZ4 mediates CTCF-dependent long-range intrachromosomal interactions on the human inactive X chromosome
Andrea H. Horakova et al.
HUMAN MOLECULAR GENETICS (2012)
YY1 Tethers Xist RNA to the Inactive X Nucleation Center
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CELL (2011)
Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region
Corinne Chureau et al.
HUMAN MOLECULAR GENETICS (2011)
A top-down analysis of Xa- and Xi-territories reveals differences of higher order structure at ≥20 Mb genomic length scales
Kathrin Teller et al.
NUCLEUS (2011)
The Long Noncoding RNA, Jpx, Is a Molecular Switch for X Chromosome Inactivation
Di Tian et al.
CELL (2010)
The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation
Dieter Pullirsch et al.
DEVELOPMENT (2010)
The Matrix Protein hnRNP U Is Required for Chromosomal Localization of Xist RNA
Yuko Hasegawa et al.
DEVELOPMENTAL CELL (2010)
DXZ4 chromatin adopts an opposing conformation to that of the surrounding chromosome and acquires a novel inactive X-specific role involving CTCF and antisense transcripts
Brian P. Chadwick
GENOME RESEARCH (2008)
SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation
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Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome
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PLOS COMPUTATIONAL BIOLOGY (2008)
Evidence that homologous X-chromosome pairing requires transcription and Ctcf protein
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NATURE GENETICS (2007)
Self-assembly and DNA binding of the blocking factor in X chromosome inactivation
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PLOS COMPUTATIONAL BIOLOGY (2007)
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JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
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Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing
Stefan Schoeftner et al.
EMBO JOURNAL (2006)
Evidence for the existence of an HP1-mediated subcode within the histone code
G Lomberk et al.
NATURE CELL BIOLOGY (2006)
A transient heterochromatic state in Xist preempts X inactivation choice without RNA stabilization
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MOLECULAR CELL (2006)
Transient homologous chromosome pairing marks the onset of X inactivation
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SCIENCE (2006)
Tsix silences Xist through modification of chromatin structure
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DEVELOPMENTAL CELL (2005)
An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
X-inactivation profile reveals extensive variability in X-linked gene expression in females
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SCIENCE (2004)
Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
A chromosomal memory triggered by Xist regulates histone methylation in X inactivation
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PLOS BIOLOGY (2004)
Scaffold attachment factor A (SAF-A) is concentrated in inactive X chromosome territories through its RGG domain
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CHROMOSOMA (2003)
Chromatin of the Barr body: histone and non-histone proteins associated with or excluded from the inactive X chromosome
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SCIENCE (2003)
Role of histone H3 lysine 27 methylation in polycomb-group silencing
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SCIENCE (2002)
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
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GENES & DEVELOPMENT (2002)
Chromosomal silencing and localization are mediated by different domains of Xist RNA
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NATURE GENETICS (2002)
Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor
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ONCOGENE (2002)
Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes
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NATURE GENETICS (2002)
Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation
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JOURNAL OF CELL BIOLOGY (2001)
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NATURE (2001)
Age- and tissue-specific variation of X chromosome inactivation ratios in normal women
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HUMAN GENETICS (2000)
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