相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Polygenic risk scores: from research tools to clinical instruments
Cathryn M. Lewis et al.
GENOME MEDICINE (2020)
Machine learning in schizophrenia genomics, a case-control study using 5,090 exomes
Yannis J. Trakadis et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2019)
Modeling Heterogeneity in the Genetic Architecture of Ethnically Diverse Groups Using Random Effect Interaction Models
Yogasudha Veturi et al.
GENETICS (2019)
Hyperparameters and tuning strategies for random forest
Philipp Probst et al.
WILEY INTERDISCIPLINARY REVIEWS-DATA MINING AND KNOWLEDGE DISCOVERY (2019)
Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis
Elliott Rees et al.
BIOLOGICAL PSYCHIATRY (2019)
Genetic architecture: the shape of the genetic contribution to human traits and disease
Nicholas J. Timpson et al.
NATURE REVIEWS GENETICS (2018)
The revival of the Gini importance?
Stefano Nembrini et al.
BIOINFORMATICS (2018)
Signatures of negative selection in the genetic architecture of human complex traits
Jian Zeng et al.
NATURE GENETICS (2018)
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
Amit V. Khera et al.
NATURE GENETICS (2018)
Male increase in brain gene expression variability is linked to genetic risk for schizophrenia
Junfang Chen et al.
TRANSLATIONAL PSYCHIATRY (2018)
ranger: A Fast Implementation of Random Forests for High Dimensional Data in C plus plus and R
Marvin N. Wright et al.
JOURNAL OF STATISTICAL SOFTWARE (2017)
Mapping the Consequences of Impaired Synaptic Plasticity in Schizophrenia through Development: An Integrative Model for Diverse Clinical Features
Jennifer K. Forsyth et al.
TRENDS IN COGNITIVE SCIENCES (2017)
The Segregated Expression of Voltage-Gated Potassium and Sodium Channels in Neuronal Membranes: Functional Implications and Regulatory Mechanisms
Mael Dumenieu et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2017)
Ion Channel Trafficking: Control of Ion Channel Density as a Target for Arrhythmias?
Elise Balse et al.
FRONTIERS IN PHYSIOLOGY (2017)
NaviGO: interactive tool for visualization and functional similarity and coherence analysis with gene ontology
Qing Wei et al.
BMC BIOINFORMATICS (2017)
Do little interactions get lost in dark random forests?
Marvin N. Wright et al.
BMC BIOINFORMATICS (2016)
Exome arrays capture polygenic rare variant contributions to schizophrenia
A. L. Richards et al.
HUMAN MOLECULAR GENETICS (2016)
Rare variants are common in schizophrenia
Jacob Gratten
NATURE NEUROSCIENCE (2016)
The statistical properties of gene-set analysis
Christiaan A. de Leeuw et al.
NATURE REVIEWS GENETICS (2016)
Calibrating random forests for probability estimation
Theresa Dankowski et al.
STATISTICS IN MEDICINE (2016)
r2VIM: A new variable selection method for random forests in genome-wide association studies
Silke Szymczak et al.
BIODATA MINING (2016)
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
Colm O'Dushlaine et al.
NATURE NEUROSCIENCE (2015)
Genetic disruption of voltage-gated calcium channels in psychiatric and neurological disorders
Samuel Heyes et al.
PROGRESS IN NEUROBIOLOGY (2015)
MAGMA: Generalized Gene-Set Analysis of GWAS Data
Christiaan A. de Leeuw et al.
PLOS COMPUTATIONAL BIOLOGY (2015)
Editorial: Ion channels and mental illness: exploring etiology and pathophysiology in major psychiatric disorders
Kathleen D. Askland
FRONTIERS IN GENETICS (2015)
Rare-Variant Association Analysis: Study Designs and Statistical Tests
Seunggeung Lee et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2014)
Probability estimation with machine learning methods for dichotomous and multicategory outcome: Theory
Jochen Kruppa et al.
BIOMETRICAL JOURNAL (2014)
Specific Sorting and Post-Golgi Trafficking of Dendritic Potassium Channels in Living Neurons
Camilla Stampe Jensen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
A polygenic burden of rare disruptive mutations in schizophrenia
Shaun M. Purcell et al.
NATURE (2014)
Large-scale genomics unveils the genetic architecture of psychiatric disorders
Jacob Gratten et al.
NATURE NEUROSCIENCE (2014)
Gene-sex interactions in schizophrenia: focus on dopamine neurotransmission
Sean C. Godar et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2014)
Mining data with random forests: current options for real-world applications
Andreas Ziegler et al.
WILEY INTERDISCIPLINARY REVIEWS-DATA MINING AND KNOWLEDGE DISCOVERY (2014)
Risk estimation using probability machines
Abhijit Dasgupta et al.
BIODATA MINING (2014)
Synthetic learning machines
Hemant Ishwaran et al.
BIODATA MINING (2014)
A comprehensive evaluation of collapsing methods using simulated and real data: excellent annotation of functionality and large sample sizes required
Carmen Dering et al.
FRONTIERS IN GENETICS (2014)
A new variable selection approach using Random Forests
A. Hapfelmeier et al.
COMPUTATIONAL STATISTICS & DATA ANALYSIS (2013)
How meaningful are heritability estimates of liability?
Penny H. Benchek et al.
HUMAN GENETICS (2013)
Evaluating empirical bounds on complex disease genetic architecture
Vineeta Agarwala et al.
NATURE GENETICS (2013)
A Hybrid Likelihood Model for Sequence-Based Disease Association Studies
Yun-Ching Chen et al.
PLOS GENETICS (2013)
Low Frequency Variants, Collapsed Based on Biological Knowledge, Uncover Complexity of Population Stratification in 1000 Genomes Project Data
Carrie B. Moore et al.
PLOS GENETICS (2013)
Major channels involved in neuropsychiatric disorders and therapeutic perspectives
Paola Imbrici et al.
Frontiers in Genetics (2013)
'Location, Location, Location': a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate
Heide Fier et al.
BIOINFORMATICS (2012)
Random forest Gini importance favours SNPs with large minor allele frequency: impact, sources and recommendations
Anne-Laure Boulesteix et al.
BRIEFINGS IN BIOINFORMATICS (2012)
Trafficking mechanisms underlying neuronal voltage-gated ion channel localization at the axon initial segment
Helene Vacher et al.
EPILEPSIA (2012)
Ion channels and schizophrenia: a gene set-based analytic approach to GWAS data for biological hypothesis testing
Kathleen Askland et al.
HUMAN GENETICS (2012)
Probability Machines Consistent Probability Estimation Using Nonparametric Learning Machines
J. D. Malley et al.
METHODS OF INFORMATION IN MEDICINE (2012)
Sex steroids and schizophrenia
Julie A. Markham
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2012)
Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes
Jacob A. Tennessen et al.
SCIENCE (2012)
Overview of random forest methodology and practical guidance with emphasis on computational biology and bioinformatics
Anne-Laure Boulesteix et al.
WILEY INTERDISCIPLINARY REVIEWS-DATA MINING AND KNOWLEDGE DISCOVERY (2012)
A Comparison of Association Methods Correcting for Population Stratification in Case-Control Studies
Chengqing Wu et al.
ANNALS OF HUMAN GENETICS (2011)
Protein Folding and Modification in the Mammalian Endoplasmic Reticulum
Ineke Braakman et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 80 (2011)
Neuronal trafficking of voltage-gated potassium channels
Camilla S. Jensen et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2011)
The Genetic Structure of the Swedish Population
Keith Humphreys et al.
PLOS ONE (2011)
Composition, assembly, and maintenance of excitable membrane domains in myelinated axons
Matthew N. Rasband
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2011)
Na+ channel beta subunits: overachievers of the ion channel family
William J. Brackenbury et al.
FRONTIERS IN PHARMACOLOGY (2011)
Rare Variant Association Analysis Methods for Complex Traits
Jennifer Asimit et al.
ANNUAL REVIEW OF GENETICS, VOL 44 (2010)
The behaviour of random forest permutation-based variable importance measures under predictor correlation
Kristin K. Nicodemus et al.
BMC BIOINFORMATICS (2010)
Assessing the Performance of Prediction Models A Framework for Traditional and Novel Measures
Ewout W. Steyerberg et al.
EPIDEMIOLOGY (2010)
Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability
Matthew S. Grubb et al.
NATURE (2010)
The axon initial segment and the maintenance of neuronal polarity
Matthew N. Rasband
NATURE REVIEWS NEUROSCIENCE (2010)
Voltage-gated sodium channel organization in neurons: Protein interactions and trafficking pathways
Christophe Leterrier et al.
NEUROSCIENCE LETTERS (2010)
Variable selection using random forests
Robin Genuer et al.
PATTERN RECOGNITION LETTERS (2010)
Dendritic ion channel trafficking and plasticity
Mala M. Shah et al.
TRENDS IN NEUROSCIENCES (2010)
Evolution of the Human Ion Channel Set
Timothy J. Jegla et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2009)
Pathways-based analyses of whole-genome association study data in bipolar disorder reveal genes mediating ion channel activity and synaptic neurotransmission
Kathleen Askland et al.
HUMAN GENETICS (2009)
Mitochondrial Dysfunction and Psychiatric Disorders
Gislaine T. Rezin et al.
NEUROCHEMICAL RESEARCH (2009)
Converging on the Origins of Axonal Ion Channel Clustering
Matthew N. Rasband
PLOS GENETICS (2009)
An Introduction to Recursive Partitioning: Rationale, Application, and Characteristics of Classification and Regression Trees, Bagging, and Random Forests
Carolin Strobl et al.
PSYCHOLOGICAL METHODS (2009)
Accounting for ancestry: population substructure and genome-wide association studies
Chao Tian et al.
HUMAN MOLECULAR GENETICS (2008)
An overview of trafficking and assembly of neurotransmitter receptors and ion channels (Review)
Blanche Schwappach
MOLECULAR MEMBRANE BIOLOGY (2008)
Abnormal indices of cell cycle activity in schizophrenia and their potential association with Oligodendrocytes
Pavel Katsel et al.
NEUROPSYCHOPHARMACOLOGY (2008)
Localization and targeting of voltage-dependent ion channels in mammalian central neurons
Helene Vacher et al.
PHYSIOLOGICAL REVIEWS (2008)
Age-dependent genetic effects on a secondary sexual trait in male Alpine ibex, Capra ibex
Achaz Von Hardenberg et al.
MOLECULAR ECOLOGY (2007)
Conservation patterns in different functional sequence categories of divergent Drosophila species
Dmitri Papatsenko et al.
GENOMICS (2006)
Gene selection and classification of microarray data using random forest -: art. no. 3
R Díaz-Uriarte et al.
BMC BIOINFORMATICS (2006)
Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
A Siepel et al.
GENOME RESEARCH (2005)
Genetics, statistics and human disease: analytical retooling for complexity
TA Thornton-Wells et al.
TRENDS IN GENETICS (2004)
The effects of human population structure on large genetic association studies
J Marchini et al.
NATURE GENETICS (2004)
Defective protein trafficking in hERG-associated hereditary long QT syndrome (LQT2): molecular mechanisms and restoration of intracellular protein processing
D Thomas et al.
CARDIOVASCULAR RESEARCH (2003)
Sodium channel Nav1.6 is localized at nodes of Ranvier, dendrites, and synapses
JH Caldwell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Gender aspects in schizophrenia: bridging the border between social and biological psychiatry
A Riecher-Rossler et al.
ACTA PSYCHIATRICA SCANDINAVICA (2000)
分享论文
