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IMMUNOLOGICAL REVIEWS (2009)
Calcium Ions Regulate K+ Uptake into Brain Mitochondria: The Evidence for a Novel Potassium Channel
Jolanta Skalska et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2009)
The VDAC1 N-terminus is essential both for apoptosis and the protective effect of anti-apoptotic proteins
Salah Abu-Hamad et al.
JOURNAL OF CELL SCIENCE (2009)
Conditional knockdown of hMRS2 results in loss of mitochondrial Mg + uptake and cell death
Martin Piskacek et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Drugs targeting the mitochondrial pore act as citotoxic and cytostatic agents in temozolomide-resistant glioma cells
Annalisa Lena et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2009)
A Protein Interaction Network for the Large Conductance Ca2+-activated K+ Channel in the Mouse Cochlea
Thandavarayan Kathiresan et al.
MOLECULAR & CELLULAR PROTEOMICS (2009)
Bad Targets the Permeability Transition Pore Independent of Bax or Bak to Switch between Ca2+-Dependent Cell Survival and Death
Soumya Sinha Roy et al.
MOLECULAR CELL (2009)
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Dunyaporn Trachootham et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Deregulation of 2 Potassium Channels in Pancreas Adenocarcinomas Implication of KV1.3 Gene Promoter Methylation
Marie Brevet et al.
PANCREAS (2009)
Gene expression profiling of the tumor microenvironment during breast cancer progression
Xiao-Jun Ma et al.
BREAST CANCER RESEARCH (2009)
A novel potassium channel in skeletal muscle mitochondria
Jolanta Skalska et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2008)
Uncoupling protein-2 accumulates rapidly in the inner mitochondrial membrane during mitochondrial reactive oxygen stress in macrophages
Tindaro M. Giardina et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2008)
The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis
Adam I. Riker et al.
BMC MEDICAL GENOMICS (2008)
Phase II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in combination with rituximab in patients with recurrent B-cell non-Hodgkin lymphoma
Barbara Pro et al.
BRITISH JOURNAL OF HAEMATOLOGY (2008)
The Warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation
Ismael Samudio et al.
CANCER RESEARCH (2008)
The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cells
Zoltan Derdak et al.
CANCER RESEARCH (2008)
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini et al.
CELL (2008)
Hypoxia increases activity of the BK-channel in the inner mitochondrial membrane and reduces activity of the permeability transition pore
Yu Cheng et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2008)
Voltage-dependent anion channel 1 is involved in endostatin-induced endothelial cell apoptosis
Shaopeng Yuan et al.
FASEB JOURNAL (2008)
Mitochondrial voltage-dependent anion channels (VDACs) as novel pharmacological targets for anti-cancer agents
Eriko Simamura et al.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES (2008)
Eag1 Expression Interferes with Hypoxia Homeostasis and Induces Angiogenesis in Tumors
Bryan R. Downie et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Hexokinase-I protection against apoptotic cell death is mediated via interaction with the voltage-dependent anion channel-1 - Mapping the site of binding
Salah Abu-Hamad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
A novel opener of large-conductance Ca2+-activated K+ (BK) channel reduces ischemic injury in rat cardiac myocytes by activating mitochondrial KCa channel
Kazuho Sakamoto et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2008)
Stromal gene expression predicts clinical outcome in breast cancer
Greg Finak et al.
NATURE MEDICINE (2008)
Differential distribution of Ca2+-activated potassium channel β4 subunit in rat brain:: Immunolocalization in neuronal mitochondria
M. Piwonska et al.
NEUROSCIENCE (2008)
Unregulated Mitochondrial GSK3β Activity Results in NADH:Ubiquinone Oxidoreductase Deficiency
Taj D. King et al.
NEUROTOXICITY RESEARCH (2008)
Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death
N. Tajeddine et al.
ONCOGENE (2008)
Hexokinase II Detachment from Mitochondria Triggers Apoptosis through the Permeability Transition Pore Independent of Voltage-Dependent Anion Channels
Federica Chiara et al.
PLOS ONE (2008)
Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes
Ildiko Szabo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Emerging roles for two-pore-domain potassium channels and their potential therapeutic impact
Douglas A. Bayliss et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Ca2+ signalling checkpoints in cancer:: remodelling Ca2+ for cancer cell proliferation and survival
H. Llewelyn Roderick et al.
NATURE REVIEWS CANCER (2008)
Mitochondrial expression of the two-pore domain TASK-3 channels in malignantly transformed and non-malignant human cells
Zoltan Rusznak et al.
VIRCHOWS ARCHIV (2008)
Diagnosing and exploiting cancer's addiction to blocks in apoptosis
Anthony G. Letai
NATURE REVIEWS CANCER (2008)
A Role for Voltage-Dependent Anion Channel Vdac1 in Polyglutamine-Mediated Neuronal Cell Death
Tanay Ghosh et al.
PLOS ONE (2007)
Vascular large conductance calcium-activated potassium channels: Functional role and therapeutic potential
Birgit Eichhorn et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2007)
Regulation of tumor cell mitochondrial Homeostasis by an organelle-specific Hsp90 chaperone network
Byoung Heon Kang et al.
CELL (2007)
Characterization and expression analysis of Paralichthys olivaceus voltage-dependent anion channel (VDAC) gene in response to virus infection
Ai-Jun Lu et al.
FISH & SHELLFISH IMMUNOLOGY (2007)
Reverse electron flow-induced ROS production is attenuated by activation of mitochondrial Ca2+-sensitive K+ channels
Andre Heinen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Uncoupling protein 2 protects testicular germ cells from hyperthermia-induced apoptosis
Keying Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Resveratrol-induced mitochondrial dysfunction and apoptosis are associated with Ca2+ and mCICR-mediated MPT activation in HepG2 cells
Xiaodong Ma et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2007)
Apoptosis regulation by Bcl-xL modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating
Chi Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Hypoxia increases BK channel activity in the inner mitochondrial membrane
Xiang Q. Gu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels
Nicholas Yagoda et al.
NATURE (2007)
Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function
Gabriel Bidaux et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Honokiol induces a necrotic cell death through the mitochondrial permeability transition pore
Ling Li et al.
CANCER RESEARCH (2007)
MAP kinase signalling pathways in cancer
A. S. Dhillon et al.
ONCOGENE (2007)
Shikonin circumvents cancer drug resistance by induction of a necroptotic death
Weidong Han et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets
Pier Paolo Piccaluga et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Mitochondrial Ca2+-induced K+ influx increases respiration and enhances ROS production while maintaining membrane potential
Andre Heinen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Transient receptor potential cation channels in disease
Bernd Nilius et al.
PHYSIOLOGICAL REVIEWS (2007)
Glycogen synthase kinase-3 (GSK3): Inflammation, diseases, and therapeutics
Richard S. Jope et al.
NEUROCHEMICAL RESEARCH (2007)
Association of Kv1.5 and Kv1.3 contributes to the major voltage-dependent K+ channel in macrophages
Ruben Vicente et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Mitochondrial reactive oxygen species and Ca2+ signaling
Cristina Camello-Almaraz et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)
Reduced Kv1.3 potassium channel expression in human prostate cancer
Mansoor Abdul et al.
JOURNAL OF MEMBRANE BIOLOGY (2006)
Cisplatin preferentially binds mitochondrial DNA and voltage-dependent anion channel protein in the mitochondrial membrane of head and neck squamous cell carcinoma: Possible role in apoptosis
Zejia Yang et al.
CLINICAL CANCER RESEARCH (2006)
Melanoma cells exhibit strong intracellular TASK-3-specific immunopositivity in both tissue sections and cell culture
K. Pocsai et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2006)
Gene expression profiling reveals stromal genes expressed in common between Barrett's esophagus and adenocarcinoma
Ying Hao et al.
GASTROENTEROLOGY (2006)
Identification of differentially expressed genes in cutaneous squamous cell carcinoma by microarray expression profiling
Ingo Nindl et al.
MOLECULAR CANCER (2006)
A pharmacologic target of G3139 in melanoma cells may be the mitochondrial VDAC
Johnathan C. Lai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The mitochondrial permeability transition from in vitro artifact to disease target
P Bernardi et al.
FEBS JOURNAL (2006)
The expression level of the voltage-dependent anion channel controls life and death of the cell
S Abu-Hamad et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
A voltage-driven switch for ion-independent signaling by ether-a-go-go K+ channels
AP Hegle et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
X chromosomal abnormalities in basal-like human breast cancer
AL Richardson et al.
CANCER CELL (2006)
Down-regulation of stem cell genes, including those in a 200-kb gene cluster at 12p13.31, is associated with in vivo differentiation of human male germ cell tumors
JE Korkola et al.
CANCER RESEARCH (2006)
The calcium-sensitive large-conductance potassium channel (BK/Maxi K) is present in the inner mitochondrial membrane of rat brain
R. M. Douglas et al.
NEUROSCIENCE (2006)
Potassium channels: New targets in cancer therapy
Antonio Felipe et al.
CANCER DETECTION AND PREVENTION (2006)
Expression of delayed rectifier potassium channels and their possible roles in proliferation of human gastric cancer cells
M Lan et al.
CANCER BIOLOGY & THERAPY (2005)
International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels
GA Gutman et al.
PHARMACOLOGICAL REVIEWS (2005)
Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation
A Cheong et al.
MOLECULAR CELL (2005)
Cardioprotective effects of estradiol include the activation of large-conductance Ca2+-activated K+ channels in cardiac mitochondria
S Ohya et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)
Gene signatures of progression and metastasis in renal cell cancer
J Jones et al.
CLINICAL CANCER RESEARCH (2005)
Molecular diversity and function of voltage-gated (Kv) potassium channels in epithelial cells
SM O'Grady et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2005)
Avicinylation (thioesterification): A protein modification that can regulate the response to oxidative and nitrosative stress
V Haridas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The voltage-dependent anion channel-1 modulates apoptotic cell death
H Zaid et al.
CELL DEATH AND DIFFERENTIATION (2005)
Differentiation of human embryonal carcinomas in vitro and in vivo reveals expression profiles relevant to normal development
RI Skotheim et al.
CANCER RESEARCH (2005)
Analysis of hypoxia-related gene expression in sarcomas and effect of hypoxia on RNA interference of vascular endothelial cell growth factor A
KY Detwiller et al.
CANCER RESEARCH (2005)
Rax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis
MG Annis et al.
EMBO JOURNAL (2005)
Identification of novel candidate oncogenes and tumor suppressors in malignant pleural mesothelioma using large-scale transcriptional profiling
GJ Gordon et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Mitochondria are intracellular magnesium stores: investigation by simultaneous fluorescent imagings in PC12 cells
T Kubota et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2005)
A novel potassium channel in lymphocyte mitochondria
I Szabò et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Reverse engineering of regulatory networks in human B cells
K Basso et al.
NATURE GENETICS (2005)
TASK-3 immunoreactivity shows differential distribution in the human gastrointestinal tract
I Kovács et al.
VIRCHOWS ARCHIV (2005)
The mitochondrial uncoupling-protein homologues
S Krauss et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Triterpenoid electrophiles (avicins) suppress heat shock protein-70 and x-linked inhibitor of apoptosis proteins in malignant cells by activation of ubiquitin machinery: Implications for proapoptotic activity
A Gaikwad et al.
CLINICAL CANCER RESEARCH (2005)
Inositol 1,4,5-trisphosphate (IP3) receptor type1 (IP3R1) modulates the acouisition of cisplatin resistance in bladder cancer cell lines
T Tsunoda et al.
ONCOGENE (2005)
Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum
SA Oakes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The glamour and gloom of glycogen synthase kinase-3
RS Jope et al.
TRENDS IN BIOCHEMICAL SCIENCES (2004)
The mitochondrial calcium uniporter is a highly selective ion channel
Y Kirichok et al.
NATURE (2004)
A proteomic approach to cisplatin resistance in the cervix squamous cell carcinoma cell line A431
A Castagna et al.
PROTEOMICS (2004)
Subcellular localization of VDAC in mitochondria and ER in the cerebellum
V Shoshan-Barmatz et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2004)
Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells
L Zhang et al.
CANCER RESEARCH (2004)
Roles of K+ channels in regulating tumour cell proliferation and apoptosis
ZG Wang
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2004)
The 2P-domain K+ channels:: role in apoptosis and tumorigenesis
AJ Patel et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2004)
Gene expression in the urinary bladder:: A common carcinoma in situ gene expression signature exists disregarding histopathological classification
L Dyrskjot et al.
CANCER RESEARCH (2004)
International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: Potassium channels
GA Gutman et al.
PHARMACOLOGICAL REVIEWS (2003)
VDAC is a conserved element of death pathways in plant and animal systems
A Godbole et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2003)
Early resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene
PC Klöhn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Expression of voltage-gated potassium channels Kv1.3 and Kv1.5 in human gliomas
K Preussat et al.
NEUROSCIENCE LETTERS (2003)
Identification of the protein-protein contact site and interaction mode of human VDAC1 with Bcl-2 family proteins
Y Shi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Apoptosis repressor with caspase domain inhibits cardiomyocyte apoptosis by reducing K+ currents
D Ekhterae et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Gene expression profiles of cutaneous B cell lymphoma
MN Storz et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2003)
Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays
CA Iacobuzio-Donahue et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Mrs2p is an essential component of the major electrophoretic Mg2+ influx system in mitochondria
M Kolisek et al.
EMBO JOURNAL (2003)
Regulation of pyruvate dehydrogenase complex activity in plant cells
A Tovar-Méndez et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2003)
Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene
D Mu et al.
CANCER CELL (2003)
Targeting ras signalling pathways in cancer therapy
J Downward
NATURE REVIEWS CANCER (2003)
Cytoprotective role of Ca2+-activated K+ channels in the cardiac inner mitochondrial membrane
WH Xu et al.
SCIENCE (2002)
Molecular proximity of Kv1.3 voltage-gated potassium channels and β1-integrins on the plasma membrane of melanoma cells:: Effects of cell adherence and channel blockers
VV Artym et al.
JOURNAL OF GENERAL PHYSIOLOGY (2002)
mtCLIC/CLIC4, an organellular chloride channel protein, is increased by DNA damage and participates in the apoptotic response to p53
E Fernández-Salas et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Prediction of central nervous system embryonal tumour outcome based on gene expression
SL Pomeroy et al.
NATURE (2002)
Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
A Rosenwald et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
A Bhattacharjee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer
JB Welsh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and bax
TH Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
D Arsenijevic et al.
NATURE GENETICS (2000)
Mitochondria and calcium: from cell signalling to cell death
MR Duchen
JOURNAL OF PHYSIOLOGY-LONDON (2000)
Electrophysiological study of a novel large pore formed by Bax and the voltage-dependent anion channel that is permeable to cytochrome c
S Shimizu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
AA Alizadeh et al.
NATURE (2000)
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