期刊
EXERCISE AND SPORT SCIENCES REVIEWS
卷 49, 期 2, 页码 67-76出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/JES.0000000000000250
关键词
exercise training; mitochondrial function; mitochondrial biogenesis; mitophagy; aging; muscle disuse; lysosomal disease
资金
- Canadian Institutes for Health Research (CIHR)
Exercise stimulates the biogenesis of mitochondria in muscle, rejuvenating mitochondrial function and promoting muscle health. While some literature suggests using pharmaceuticals to enhance mitochondria, exercise proves to be a more effective and natural approach in improving mitochondrial function.
Exercise stimulates the biogenesis of mitochondria in muscle. Some literature supports the use of pharmaceuticals to enhance mitochondria as a substitute for exercise. We provide evidence that exercise rejuvenates mitochondrial function, thereby augmenting muscle health with age, in disease, and in the absence of cellular regulators. This illustrates the power of exercise to act as mitochondrial medicine in muscle.
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