期刊
EUROPEAN RADIOLOGY
卷 31, 期 11, 页码 8578-8585出版社
SPRINGER
DOI: 10.1007/s00330-021-07927-5
关键词
Esophagus; Magnetic resonance imaging; Fundoplication; contrast agent
资金
- Medical University of Vienna
In evaluating image quality in MR swallowing, using LumiVision (R) undiluted showed similar results to gadolinium-buttermilk mixture, while LumiVision (R) water mixture performed significantly worse. Therefore, oral ingestion of LumiVision (R) undiluted is recommended for MR swallowing examinations.
Objectives To evaluate image quality by first use of LumiVision (R) in dynamic MR swallowing, a contrast medium consisting of biological substances versus a gadolinium-buttermilk mixture in patients who underwent Nissen fundoplication due to gastroesophageal reflux disease (GERD). Methods The protocol of this retrospective study was approved by the local Institutional Review Board. A hundred twenty-nine patients (146 examinations) underwent a dynamic MR swallowing study (at 1.5 T or 3.0 T) and received an oral contrast agent. Two readers evaluated the distention of the esophagus, contrast, and traceability of the bolus in a 3-point scale. A steady-state coherent sequence (B-FFE, TrueFISP) was used. The patients were divided into 3 different groups: 53 patients received gadolinium chelate (Dotarem (R))-buttermilk mixture (GBM) in a dilution of 1:40 as an oral contrast agent; 44 patients received LumiVision (R) water mixture (LWM) in a dilution of 1:1 and 49 patients received LumiVision (R) (L) undiluted. Results GBM showed significantly better results in overall evaluation for both readers in contrast to LWM (p = .003, p = .002). L also reached significantly better results in overall evaluation than LWM in both readers (p = .004, p = .042). There was no significant difference in the overall evaluation between L and GBM (p = .914, p = .376).According to Landis and Koch, interobserver agreement was substantial (Cohen's kappa = 0.738) between both readers. Conclusion LumiVision (R) undiluted showed equal image quality compared to gadolinium-buttermilk mixture. The constellation of LumiVision (R) water mixture led to a clearly negative result in relation to the image quality compared to LumiVision (R) undiluted. Therefore, oral ingestion of LumiVision (R) undiluted is recommended for MR swallowing examinations.
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