期刊
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
卷 48, 期 13, 页码 4171-4188出版社
SPRINGER
DOI: 10.1007/s00259-021-05259-6
关键词
X-ray imaging; Phase contrast imaging; Grating interferometer; Grating interferometry; CT; Computed tomography; Phase contrast tomography; Quantitative imaging; Electron density; Effective atomic number
资金
- Projekt DEAL
- European Research Council [AdG 695045]
- German Research Foundation (DFG) under the Gottfried Wilhelm Leibniz Program
- German Research Foundation (DFG) [GRK 2274]
Quantitative nature of biomedical imaging data is becoming increasingly important with the advancements in data science. Grating-based phase contrast computed tomography (GBPC-CT) is a phase contrast micro-CT imaging technique that offers high soft tissue contrast and high spatial resolution, and allows for quantitative determination of electron density and effective atomic number using laboratory X-ray sources. This review article focuses on the application of quantitative GBPC-CT in biomedical field.
The ability of biomedical imaging data to be of quantitative nature is getting increasingly important with the ongoing developments in data science. In contrast to conventional attenuation-based X-ray imaging, grating-based phase contrast computed tomography (GBPC-CT) is a phase contrast micro-CT imaging technique that can provide high soft tissue contrast at high spatial resolution. While there is a variety of different phase contrast imaging techniques, GBPC-CT can be applied with laboratory X-ray sources and enables quantitative determination of electron density and effective atomic number. In this review article, we present quantitative GBPC-CT with the focus on biomedical applications.
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