4.7 Review

Specific non-genetic IAP-based protein erasers (SNIPERs) as a potential therapeutic strategy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Chemistry, Medicinal

Novel strategies targeting bromodomain-containing protein 4 (BRD4) for cancer drug discovery

Dailin Liang et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)

Review Chemistry, Medicinal

Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges

Scott D. Edmondson et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2019)

Article Biotechnology & Applied Microbiology

Targeted protein degradation: expanding the toolbox

Matthieu Schapira et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

Meeting Abstract Oncology

ARV-471, an oral estrogen receptor PROTAC degrader for breast cancer

J. J. Flanagan et al.

CANCER RESEARCH (2019)

Article Biochemistry & Molecular Biology

Targeting the C481S Ibrutinib-Resistance Mutation in Bruton's Tyrosine Kinase Using PROTAC-Mediated Degradation

Alexandru D. Buhimschi et al.

BIOCHEMISTRY (2018)

Article Biochemistry & Molecular Biology

Derivatization of inhibitor of apoptosis protein (IAP) ligands yields improved inducers of estrogen receptor degradation

Nobumichi Ohoka et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Article Chemistry, Medicinal

Targeting the Allosteric Site of Oncoprotein BCR-ABL as an Alternative Strategy for Effective Target Protein Degradation

Kenichiro Shimokawa et al.

ACS MEDICINAL CHEMISTRY LETTERS (2017)

Article Chemistry, Medicinal

Development of a peptide-based inducer of protein degradation targeting NOTCH1

Nobumichi Ohoka et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)

Article Chemistry, Multidisciplinary

Discovery of Small Molecules that Induce the Degradation of Huntingtin

Shusuke Tomoshige et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Multidisciplinary

Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL

Ashton C. Lai et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Review Chemistry, Multidisciplinary

Small-Molecule PROTACS: New Approaches to Protein Degradation

Momar Toure et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Chemistry, Medicinal

Development of a peptide-based inducer of nuclear receptors degradation

Yosuke Demizu et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)

Article Chemistry, Medicinal

Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand

Yosuke Demizu et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)

Review Biotechnology & Applied Microbiology

Small molecules, big targets: drug discovery faces the protein-protein interaction challenge

Duncan E. Scott et al.

NATURE REVIEWS DRUG DISCOVERY (2016)

Article Multidisciplinary Sciences

PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer

Kanak Raina et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Biochemistry & Molecular Biology

HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of Halo Tag Fusion Proteins

Dennis L. Buckley et al.

ACS CHEMICAL BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4

Michael Zengerle et al.

ACS CHEMICAL BIOLOGY (2015)

Review Biochemistry & Molecular Biology

Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation

Emil Bulatov et al.

BIOCHEMICAL JOURNAL (2015)

Review Biochemistry & Molecular Biology

Targeting the ubiquitin pathway for cancer treatment

Jia Liu et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2015)

Article Biochemistry & Molecular Biology

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

Jing Lu et al.

CHEMISTRY & BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Catalytic in vivo protein knockdown by small-molecule PROTACs

Daniel P. Bondeson et al.

NATURE CHEMICAL BIOLOGY (2015)

Article Multidisciplinary Sciences

Phthalimide conjugation as a strategy for in vivo target protein degradation

Georg E. Winter et al.

SCIENCE (2015)

Review Chemistry, Multidisciplinary

Small-Molecule Control of Intracellular Protein Levels through Modulation of the Ubiquitin Proteasome System

Dennis L. Buckley et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Chemistry, Multidisciplinary

Privileged Structures: Efficient Chemical Navigators toward Unexplored Biologically Relevant Chemical Spaces

Jonghoon Kim et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Review Pharmacology & Pharmacy

Small-molecule SMAC mimetics as new cancer therapeutics

Longchuan Bai et al.

PHARMACOLOGY & THERAPEUTICS (2014)

Article Chemistry, Medicinal

Design and synthesis of estrogen receptor degradation inducer based on a protein knockdown strategy

Yosuke Demizu et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

Article Chemistry, Medicinal

Double protein knockdown of cIAP1 and CRABP-II using a hybrid molecule consisting of ATRA and IAPs antagonist

Yukihiro Itoh et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)

Article Biochemistry & Molecular Biology

Development of target protein-selective degradation inducer for protein knockdown

Yukihiro Itoh et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Design, synthesis and biological evaluation of nuclear receptor-degradation inducers

Yukihiro Itoh et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2011)

Review Gastroenterology & Hepatology

Nuclear Receptors in Liver Disease

Martin Wagner et al.

HEPATOLOGY (2011)

Review Pharmacology & Pharmacy

Nuclear receptors as drug targets for metabolic disease

Ira G. Schulman

ADVANCED DRUG DELIVERY REVIEWS (2010)

Review Biochemistry & Molecular Biology

Chemical Inducers of Targeted Protein Degradation

Kanak Raina et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Nanoscience & Nanotechnology

siRNA applications in nanomedicine

Talar Tokatlian et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2010)

Review Chemistry, Medicinal

Targeting inhibitor of apoptosis proteins for therapeutic intervention

Chudi Ndubaku et al.

FUTURE MEDICINAL CHEMISTRY (2009)

Article Multidisciplinary Sciences

Direct inhibition of the NOTCH transcription factor complex

Raymond E. Moellering et al.

NATURE (2009)

Article Chemistry, Medicinal

Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics

Ashley R. Schneekloth et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)

Article Biochemistry & Molecular Biology

Small molecules destabilize cIAP1 by activating auto-ubiquitylation

Keiko Sekine et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Multidisciplinary Sciences

Overcoming retinoic acid-resistance of mammary carcinomas by diverting retinoic acid from PPARβ/δ to RAR

Thaddeus T. Schug et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Multidisciplinary Sciences

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

James A. Wells et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

Brendan P. Eckelman et al.

EMBO REPORTS (2006)

Article Biochemistry & Molecular Biology

The inhibitor of apoptosis protein fusion c-IAP2•MALT1 stimulates NF-κB activation independently of TRAF1 AND TRAF2

Eugene Varfolomeev et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases

BP Eckelman et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemical Research Methods

Development of protacs to target cancer-promoting proteins for ubiquitination and degradation

KM Sakamoto et al.

MOLECULAR & CELLULAR PROTEOMICS (2003)

Review Cell Biology

IAP proteins: Blocking the road to death's door

GS Salvesen et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)

Article Multidisciplinary Sciences

Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

KM Sakamoto et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

XIAP: Apoptotic brake and promising therapeutic target

M Holcik et al.

APOPTOSIS (2001)