期刊
ENVIRONMENTAL POLLUTION
卷 276, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.envpol.2021.116725
关键词
Ionic liquids; Glutathione; Nicotinamide adenine dinucleotide; Cysteine; Reactive oxygen species; Tetrahymena pyriformis
资金
- GDAS' Project of Science and Technology Development [2020GDASYL-20200103018, 2017GDASCX-0102, 2018GDASCX-0102]
- National Natural Science Foundation of China [21901048]
- Nanyue Talent Fund [GDIMYET20190105]
The study evaluated the biotoxicities of imidazolium-based ILs in Tetrahymena pyriformis and investigated IL detoxification by adding glutathione, cysteine, and NADH, with results showing that NADH exhibited the best detoxification ability.
Ionic liquids (ILs), also known as green solvents, are widely acknowledged in several fields, such as chemical separation, synthesis, and electrochemistry, owing to their excellent physiochemical properties. However, their poor biodegradability may lead to environmental and health risks, posing a severe threat to humans, thus requiring further research. In this study, the biotoxicities of the imidazolium-based ILs were evaluated in Tetrahymena pyriformis. Moreover, IL detoxification was investigated by addition of glutathione (GSH), cysteine, and nicotinamide adenine dinucleotide (NADH). Reactive oxygen species (ROS) initiated by different IL types caused damage to Tetrahymena, while glutathione, cysteine, and NADH eliminated ROS, achieving the detoxification purposes. Detoxification results showed that NADH exhibited the best detoxification ability, followed by glutathione and cysteine. Finally, RT-PCR results suggested that metallothionein might have participated in IL detoxification. (C) 2020 The Author(s).
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