期刊
ENDOCRINOLOGY
卷 162, 期 8, 页码 -出版社
ENDOCRINE SOC
DOI: 10.1210/endocr/bqab082
关键词
vasopressin; oxytocin; hypertension; heart failure
资金
- National Institutes of Health/National Institute on Aging [AG020494]
- National Institutes of Health/National Heart Lung and Blood Institute [P01 088052, R01 HL142341, R01 155977]
AVP and OXY are released by magnocellular neurosecretory cells projecting to the posterior pituitary. While traditionally not believed to contribute to basal cardiovascular function, recent studies suggest potential re-evaluation as evidence indicates their role in cardiovascular pathophysiology.
Arginine vasopressin (AVP) and oxytocin (OXY) are released by magnocellular neurosecretory cells that project to the posterior pituitary. While AVP and OXY currently receive more attention for their contributions to affiliative behavior, this mini-review discusses their roles in cardiovascular function broadly defined to include indirect effects that influence cardiovascular function.The traditional view is that neither AVP nor OXY contributes to basal cardiovascular function, although some recent studies suggest that this position might be re-evaluated. More evidence indicates that adaptations and neuroplasticity of AVP and OXY neurons contribute to cardiovascular pathophysiology.
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