Obesity: Overview of Weight Management

Introduction: Obesity is a chronic illness that requires a multifaceted personalized treatment approach. Methods & Findings: Using current guidelines and recent studies in weight management, this article reviews the multiple components of weight management: lifestyle intervention (dietary intervention, physical activity, and behavioral interventions), pharmacotherapy, endoscopic procedures, and surgical procedures. This review briefly discusses specific diets and dietary strategies, compensatory mechanisms acting against weight loss, recent changes to Food and Drug Administration approved antiobesity medications, and technological advances in weight management delivery. Conclusion: Current literature is lacking large studies on the safety and efficacy of combination therapies involving pharmacotherapy plus 1 or more procedures. (C) 2021 AACE. Published by Elsevier Inc. All rights reserved.

Automated summary

This article reviews the multifaceted personalized treatment approach for obesity, including lifestyle interventions, pharmacotherapy, endoscopic procedures, and surgical procedures. However, current literature lacks large studies on the safety and efficacy of combination therapies involving pharmacotherapy plus surgical procedures.