4.7 Review

Lipid metabolism in cancer: New perspectives and emerging mechanisms

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Myeloma-Modified Adipocytes Exhibit Metabolic Dysfunction and a Senescence-Associated Secretory Phenotype

Heather Fairfield et al.

Summary: Interactions between bone marrow adipocytes (BMAds) and myeloma cells play a significant role in the pathogenesis and treatment of multiple myeloma. Studies show that myeloma cells reduce bone marrow adipose tissue (BMAT) and induce senescence and metabolic changes in BMAds.

CANCER RESEARCH (2021)

Article Oncology

Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis

Lindsay A. Broadfield et al.

Summary: The study indicates that high-fat intake can lead to metabolic changes in the liver, including increased glucose uptake and lactate secretion. Furthermore, the research suggests that fat can induce metabolic changes in nontransformed liver cells similar to those found in hepatocellular carcinoma (HCC).

CANCER RESEARCH (2021)

Article Biochemistry & Molecular Biology

Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal

Wan-Yang Sun et al.

Summary: By hydrolyzing 15-HpETE-PE, iPLA(2)beta prevents ferroptosis, while its dysfunction increases cellular sensitivity to ferroptosis. Mutations in PLA2G6 gene may be implicated in the pathogenesis of Parkinson's disease.

NATURE CHEMICAL BIOLOGY (2021)

Article Medical Laboratory Technology

Lipid metabolism changes in patients with severe COVID-19

Yi Li et al.

Summary: This study found that in severe COVID-19 patients, survivors showed an increasing trend in LDL-C, TC, HDL-C, and apoA-I, while non-survivors showed a decreasing trend. The concentrations of HDL-C and apoA-I were inversely correlated with CRP, length of hospital stay of survivors, and disease severity scores. High CRP/HDL-C ratio was significantly associated with an increase in mortality and a poor prognosis.

CLINICA CHIMICA ACTA (2021)

Article Biochemistry & Molecular Biology

Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity

Yurena Vivas-Garcia et al.

MOLECULAR CELL (2020)

Review Cell Biology

Greasing the Wheels of the Cancer Machine: The Role of Lipid Metabolism in Cancer

Marteinn Thor Snaebjornsson et al.

CELL METABOLISM (2020)

Article Endocrinology & Metabolism

Myeloma Cells Down-Regulate Adiponectin in Bone Marrow Adipocytes Via TNF-Alpha

Emma Morris et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2020)

Article Biochemistry & Molecular Biology

Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells

Leslie E. Lupien et al.

JOURNAL OF LIPID RESEARCH (2020)

Article Multidisciplinary Sciences

Metabolic heterogeneity confers differences in melanoma metastatic potential

Alpaslan Tasdogan et al.

NATURE (2020)

Article Public, Environmental & Occupational Health

Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis

Catherine de Martel et al.

LANCET GLOBAL HEALTH (2020)

Article Pharmacology & Pharmacy

Hypolipidemia is associated with the severity of COVID-19

Xiuqi Wei et al.

JOURNAL OF CLINICAL LIPIDOLOGY (2020)

Article Oncology

Targeting Fatty Acid Oxidation to Promote Anoikis and Inhibit Ovarian Cancer Progression

Brandon T. Sawyer et al.

MOLECULAR CANCER RESEARCH (2020)

Article Oncology

Perhexiline Demonstrates FYN-mediated Antitumor Activity in Glioblastoma

Shiva Kant et al.

MOLECULAR CANCER THERAPEUTICS (2020)

Article Multidisciplinary Sciences

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

Steven Zhao et al.

NATURE (2020)

Article Pathology

Fatty change of the liver microenvironment influences the metastatic potential of colorectal cancer

Satoshi Masaki et al.

INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2020)

Review Oncology

Statins as Anticancer Agents in the Era of Precision Medicine

Joseph Longo et al.

CLINICAL CANCER RESEARCH (2020)

Article Multidisciplinary Sciences

Lymph protects metastasizing melanoma cells from ferroptosis

Jessalyn M. Ubellacker et al.

NATURE (2020)

Article Multidisciplinary Sciences

PLA2G6 guards placental trophoblasts against ferroptotic injury

Ofer Beharier et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Biochemistry & Molecular Biology

Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity

Alison E. Ringel et al.

Review Pharmacology & Pharmacy

Bioactive lysolipids in cancer and angiogenesis

Yu Hisano et al.

PHARMACOLOGY & THERAPEUTICS (2019)

Article Oncology

CD36 mediates palmitate acid-induced metastasis of gastric cancer via AKT/GSK-3/-catenin pathway

Jiaomeng Pan et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

Article Multidisciplinary Sciences

Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death

Javier Garcia-Bermudez et al.

NATURE (2019)

Review Biotechnology & Applied Microbiology

AMP-activated protein kinase: the current landscape for drug development

Gregory R. Steinberg et al.

NATURE REVIEWS DRUG DISCOVERY (2019)

Article Multidisciplinary Sciences

Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation

Choong-kun Lee et al.

SCIENCE (2019)

Article Oncology

A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression

Francesca R. Auciello et al.

CANCER DISCOVERY (2019)

Article Cell Biology

Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment

Xingzhe Ma et al.

CELL METABOLISM (2019)

Meeting Abstract Oncology

A phase I open label study evaluating VT1021 in patients with advanced solid tumors.

Michael Cieslewicz et al.

JOURNAL OF CLINICAL ONCOLOGY (2019)

Article Multidisciplinary Sciences

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

Weimin Wang et al.

NATURE (2019)

Article Multidisciplinary Sciences

An allosteric mechanism for potent inhibition of human ATP-citrate lyase

Jia Wei et al.

NATURE (2019)

Review Biochemistry & Molecular Biology

Phenformin as an Anticancer Agent: Challenges and Prospects

Ma Eugenia Garcia Rubino et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Biochemistry & Molecular Biology

Emerging roles of low-density lipoprotein in the development and treatment of breast cancer

Xuefeng Guan et al.

LIPIDS IN HEALTH AND DISEASE (2019)

Article Pharmacology & Pharmacy

Synthesis and anti-cancer activity of ND-646 and its derivatives as acetyl-CoA carboxylase 1 inhibitors

En-Qin Li et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2019)

Review Immunology

Dendritic Cell Metabolism and Function in Tumors

Paolo Giovanelli et al.

TRENDS IN IMMUNOLOGY (2019)

Article Cell Biology

The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma

Wen-Hsuan Yang et al.

CELL REPORTS (2019)

Article Oncology

Are 90% of deaths from cancer caused by metastases?

Hanna Dillekas et al.

CANCER MEDICINE (2019)

Article Virology

Virus Impact on Lipids and Membranes

Ellen Ketter et al.

ANNUAL REVIEW OF VIROLOGY, VOL 6, 2019 (2019)

Article Oncology

4T1 Mammary Carcinoma Colonization of Metastatic Niches Is Accelerated by Obesity

Gabriela Coeli Menezes Evangelista et al.

FRONTIERS IN ONCOLOGY (2019)

Article Multidisciplinary Sciences

FSP1 is a glutathione-independent ferroptosis suppressor

Sebastian Doll et al.

NATURE (2019)

Article Multidisciplinary Sciences

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

Kirill Bersuker et al.

NATURE (2019)

Review Chemistry, Medicinal

Ferroptosis: The Greasy Side of Cell Death

Jose Pedro Friedmann Angeli et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2019)

Review Oncology

Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion

Jose Pedro Friedmann Angeli et al.

NATURE REVIEWS CANCER (2019)

Article Medicine, Research & Experimental

Fatty acid-induced CD36 expression via O-GlcNAcylation drives gastric cancer metastasis

Mingzuo Jiang et al.

THERANOSTICS (2019)

Article Biochemistry & Molecular Biology

Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State

Leslie Magtanong et al.

CELL CHEMICAL BIOLOGY (2019)

Article Cell Biology

Etomoxir Inhibits Macrophage Polarization by Disrupting CoA Homeostasis

Ajit S. Divakaruni et al.

CELL METABOLISM (2018)

Review Cell Biology

Understanding the diversity of membrane lipid composition

Takeshi Harayama et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression

Xiangming Ji et al.

ONCOGENE (2018)

Article Biochemistry & Molecular Biology

Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis

Andras Ladanyi et al.

ONCOGENE (2018)

Article Multidisciplinary Sciences

Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy

Ali Talebi et al.

NATURE COMMUNICATIONS (2018)

Review Immunology

Bioactive Lipids and Chronic Inflammation: Managing the Fire Within

Valerio Chiurchiu et al.

FRONTIERS IN IMMUNOLOGY (2018)

Review Chemistry, Medicinal

ATP citrate lyase (ACLY) inhibitors: An anti-cancer strategy at the crossroads of glucose and lipid metabolism

Carlotta Granchi

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)

Review Biochemistry & Molecular Biology

A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization

Miguel F. Sanmamed et al.

Article Oncology

Obesity promotes the expansion of metastasis-initiating cells in breast cancer

Melanie Bousquenaud et al.

BREAST CANCER RESEARCH (2018)

Article Multidisciplinary Sciences

Targeting metastasis-initiating cells through the fatty acid receptor CD36

Gloria Pascual et al.

NATURE (2017)

Article Biochemistry & Molecular Biology

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll et al.

NATURE CHEMICAL BIOLOGY (2017)

Review Biochemistry & Molecular Biology

Cancer heterogeneity is not compatible with one unique cancer cell metabolic map

A. Strickaert et al.

ONCOGENE (2017)

Article Multidisciplinary Sciences

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

Matthew J. Hangauer et al.

NATURE (2017)

Review Cell Biology

The mystery of membrane organization: composition, regulation and roles of lipid rafts

Erdinc Sezgin et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Article Oncology

Exogenous lipids promote the growth of breast cancer cells via CD36

Jing Zhao et al.

ONCOLOGY REPORTS (2017)

Article Oncology

Lipid degradation promotes prostate cancer cell survival

Harri M. Itkonen et al.

ONCOTARGET (2017)

Review Medicine, General & Internal

Adiposity and cancer at major anatomical sites: umbrella review of the literature

Maria Kyrgiou et al.

BMJ-BRITISH MEDICAL JOURNAL (2017)

Review Medicine, General & Internal

Adiposity and cancer at major anatomical sites: umbrella review of the literature

Maria Kyrgiou et al.

BMJ-BRITISH MEDICAL JOURNAL (2017)

Article Geriatrics & Gerontology

The mitochondrial metabolic reprogramming agent trimetazidine as an 'exercise mimetic' in cachectic C26-bearing mice

Francesca Molinari et al.

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2017)

Review Biochemistry & Molecular Biology

Abdominal obesity and colorectal cancer risk: systematic review and meta-analysis of prospective studies

Yunlong Dong et al.

BIOSCIENCE REPORTS (2017)

Article Medicine, Research & Experimental

Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells

Yuan Yuan Wang et al.

JCI INSIGHT (2017)

Article Biochemistry & Molecular Biology

Oncogenic PI3K and K-Ras stimulate de novo lipid synthesis through mTORC1 and SREBP

S. J. H. Ricoult et al.

ONCOGENE (2016)

Review Biochemistry & Molecular Biology

Recent progress in the discovery and development of stearoyl CoA desaturase inhibitors

Yoshikazu Uto

CHEMISTRY AND PHYSICS OF LIPIDS (2016)

Review Peripheral Vascular Disease

Bempedoic Acid (ETC-1002): an Investigational Inhibitor of ATP Citrate Lyase

Ozlem Bilen et al.

CURRENT ATHEROSCLEROSIS REPORTS (2016)

Review Endocrinology & Metabolism

Desaturase and elongase-limiting endogenous long-chain polyunsaturated fatty acid biosynthesis

Ji Yao Zhang et al.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2016)

Review Biochemistry & Molecular Biology

Lipid desaturation - the next step in targeting lipogenesis in cancer?

Barrie Peck et al.

FEBS JOURNAL (2016)

News Item Biotechnology & Applied Microbiology

Cancer anabolic metabolism inhibitors move into clinic

Ken Garber

NATURE BIOTECHNOLOGY (2016)

Article Biochemistry & Molecular Biology

Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer

Roman Camarda et al.

NATURE MEDICINE (2016)

Article Multidisciplinary Sciences

Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats

Geraldine Harriman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Cell Biology

Ferrootosis: Death by Lipid Peroxidation

Wan Seok Yang et al.

TRENDS IN CELL BIOLOGY (2016)

Article Multidisciplinary Sciences

Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

Stephen L. Pinkosky et al.

NATURE COMMUNICATIONS (2016)

Article Multidisciplinary Sciences

FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth

Felipe Slebe et al.

NATURE COMMUNICATIONS (2016)

Review Oncology

Lipid metabolic reprogramming in cancer cells

S. Beloribi-Djefaflia et al.

ONCOGENESIS (2016)

Review Oncology

The metabolic fate of acetate in cancer

Zachary T. Schug et al.

NATURE REVIEWS CANCER (2016)

Review Oncology

The multifaceted roles of fatty acid synthesis in cancer

Florian Roehrig et al.

NATURE REVIEWS CANCER (2016)

Review Oncology

The interplay between cell signalling and the mevalonate pathway in cancer

Peter J. Mullen et al.

NATURE REVIEWS CANCER (2016)

Article Biochemistry & Molecular Biology

Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2+ Breast Cancer

Yazan Alwarawrah et al.

CELL CHEMICAL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis

Juan R. Cubillos-Ruiz et al.

Article Biochemistry & Molecular Biology

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

Ping-Chih Ho et al.

Article Biochemistry & Molecular Biology

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

Chih-Hao Chang et al.

Article Biochemistry & Molecular Biology

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

Santiago Zelenay et al.

Review Cell Biology

Acetyl Coenzyme A: A Central Metabolite and Second Messenger

Federico Pietrocola et al.

CELL METABOLISM (2015)

Article Endocrinology & Metabolism

Aberrant Lipid Metabolism in Anaplastic Thyroid Carcinoma Reveals Stearoyl CoA Desaturase 1 as a Novel Therapeutic Target

Christina A. von Roemeling et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2015)

Article Multidisciplinary Sciences

Oxidative stress inhibits distant metastasis by human melanoma cells

Elena Piskounova et al.

NATURE (2015)

Article Multidisciplinary Sciences

CREB pathway links PGE2 signaling with macrophage polarization

Bing Luan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma

Fabienne Guillaumond et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Cell Biology

SLC7A11 expression is associated with seizures and predicts poor survival in patients with malignant glioma

Stephanie M. Robert et al.

SCIENCE TRANSLATIONAL MEDICINE (2015)

Article Multidisciplinary Sciences

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

Nikolaos Patsoukis et al.

NATURE COMMUNICATIONS (2015)

Article Biochemistry & Molecular Biology

Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition

L. Jiang et al.

ONCOGENE (2015)

Article Biochemistry & Molecular Biology

Regulation of Ferroptotic Cancer Cell Death by GPX4

Wan Seok Yang et al.

Article Oncology

Lipid Catabolism via CPT1 as a Therapeutic Target for Prostate Cancer

Isabel R. Schlaepfer et al.

MOLECULAR CANCER THERAPEUTICS (2014)

Article Cell Biology

Metabolic control of YAP and TAZ by the mevalonate pathway

Giovanni Sorrentino et al.

NATURE CELL BIOLOGY (2014)

Article Cell Biology

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Jose Pedro Friedmann Angeli et al.

NATURE CELL BIOLOGY (2014)

Article Immunology

Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages

Stanley Ching-Cheng Huang et al.

NATURE IMMUNOLOGY (2014)

Article Biochemistry & Molecular Biology

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells

Luciana Berod et al.

NATURE MEDICINE (2014)

Review Cell Biology

Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment

Daniel Ackerman et al.

TRENDS IN CELL BIOLOGY (2014)

Review Immunology

From monocytes to M1/M2 macrophages: phenotypical vs. functional differentiation

Paola Italiani et al.

FRONTIERS IN IMMUNOLOGY (2014)

Review Oncology

Cancer cachexia: understanding the molecular basis

Josep M. Argiles et al.

NATURE REVIEWS CANCER (2014)

Article Oncology

Stearoyl-CoA Desaturase 1 Is a Novel Molecular Therapeutic Target for Clear Cell Renal Cell Carcinoma

Christina A. von Roemeling et al.

CLINICAL CANCER RESEARCH (2013)

Article Biochemistry & Molecular Biology

Towards Lipidomics of Low-Abundant Species for Exploring Tumor Heterogeneity Guided by High-Resolution Mass Spectrometry Imaging

Jonathan Cimino et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)

Article Clinical Neurology

Up-regulation of USP2a and FASN in gliomas correlates strongly with glioma grade

Bang-Bao Tao et al.

JOURNAL OF CLINICAL NEUROSCIENCE (2013)

Article Oncology

Carnitine-Acyltransferase System Inhibition, Cancer Cell Death, and Prevention of Myc-Induced Lymphomagenesis

Annalisa Pacilli et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)

Article Multidisciplinary Sciences

Comprehensivemolecular characterization of clear cell renal cell carcinoma

Chad J. Creighton et al.

NATURE (2013)

Article Multidisciplinary Sciences

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids

Jurre J. Kamphorst et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Medicine, General & Internal

Risk of colorectal cancer after initiation of orlistat: matched cohort study

Jin-Liern Hong et al.

BMJ-BRITISH MEDICAL JOURNAL (2013)

Article Biochemistry & Molecular Biology

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon et al.

Review Immunology

Regulation of Immune Responses by Prostaglandin E-2

Pawel Kalinski

JOURNAL OF IMMUNOLOGY (2012)

Article Biochemistry & Molecular Biology

The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and-2

Jenson Qi et al.

JOURNAL OF LIPID RESEARCH (2012)

Review Immunology

Metabolic checkpoints in activated T cells

Ruoning Wang et al.

NATURE IMMUNOLOGY (2012)

Article Multidisciplinary Sciences

Inhibition of Fatty Acid Metabolism Reduces Human Myeloma Cells Proliferation

Jose Manuel Tirado-Velez et al.

PLOS ONE (2012)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Review Chemistry, Multidisciplinary

Free Radical Lipid Peroxidation: Mechanisms and Analysis

Huiyong Yin et al.

CHEMICAL REVIEWS (2011)

Editorial Material Chemistry, Medicinal

Carnitine Palmitoyltransferase (CPT) Modulators: A Medicinal Chemistry Perspective on 35 Years of Research

Simona M. Ceccarelli et al.

JOURNAL OF MEDICINAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

Kristin M. Nieman et al.

NATURE MEDICINE (2011)

Review Multidisciplinary Sciences

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

Robert D. Schreiber et al.

SCIENCE (2011)

Review Oncology

Fatty acid synthase as a potential therapeutic target in cancer

Richard Flavin et al.

FUTURE ONCOLOGY (2010)

Article Medicine, Research & Experimental

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

Ismael Samudio et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Biochemistry & Molecular Biology

Lipid accumulation and dendritic cell dysfunction in cancer

Donna L. Herber et al.

NATURE MEDICINE (2010)

Article Multidisciplinary Sciences

Dysregulation of the mevalonate pathway promotes transformation

James W. Clendening et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Multidisciplinary Sciences

Lipid Rafts As a Membrane-Organizing Principle

Daniel Lingwood et al.

SCIENCE (2010)

Article Chemistry, Medicinal

Discovery of potent, selective, orally bioavailable Stearoyl-CoA desaturase 1 inhibitors

Gang Liu et al.

JOURNAL OF MEDICINAL CHEMISTRY (2007)

Article Oncology

A phase II study of ABT-510 (thrombospondin-1 analog) for the treatment of metastatic melanoma

Svetomir N. Markovic et al.

AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS (2007)

Article Biochemistry & Molecular Biology

Thrombospondin-1 inhibits nitric oxide signaling via CD36 by inhibiting myristic acid uptake

Jeff S. Isenberg et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Cardiac & Cardiovascular Systems

Perhexiline

Houman Ashrafian et al.

CARDIOVASCULAR DRUG REVIEWS (2007)

Review Developmental Biology

Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults

GC Burdge et al.

REPRODUCTION NUTRITION DEVELOPMENT (2005)

Article Biochemistry & Molecular Biology

Identification and expression of mammalian long-chain PUFA elongation enzymes

AE Leonard et al.

LIPIDS (2002)

Review Biochemistry & Molecular Biology

Thrombospondins and tumor angiogenesis

F de Fraipont et al.

TRENDS IN MOLECULAR MEDICINE (2001)