4.7 Review

Application of bacteriophage-derived endolysins to combat streptococcal disease: current State and perspectives

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Summary: Endolysins, as a promising new class of antimicrobials, have shown effectiveness in various animal models against bacterial infections in different organs and tissues. However, challenges such as immunogenicity, circulation half-life, and specific targeting and penetration properties still need to be addressed for their systemic application.

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