期刊
CLINICAL ORAL IMPLANTS RESEARCH
卷 32, 期 6, 页码 767-775出版社
WILEY
DOI: 10.1111/clr.13746
关键词
animal experiments; biomaterials; bone substitutes; growth factors; sinus floor elevation
资金
- Neodent Company [PAP 2508.17]
The study found that the addition of BM and the type of implant surface did not have a significant impact on osseointegration in areas grafted with sintered deproteinized bovine bone at high temperatures. There were no differences observed in the quantity of mineralized tissues around the implants or the bone-implant contact between the different groups assessed.
Objectives To assess the influence of two different implant surfaces on osseointegration in maxillary sinuses of rabbits previously grafted with deproteinized bovine bone (DBB) associated or not with fresh bone marrow (BM). Material and methods Sixteen New Zealand albino rabbits (males, 3.5/4.5 kg and 9-12 months old) were randomly divided into two groups with 8 rabbits each, according to the type of association of biomaterials used to fill the animals' maxillary sinuses: DBB (Deproteinized Bovine Bone) and DBB/BM (Deproteinized bovine bone associated with fresh autologous bone marrow). Ninety (90) days following the grafting procedure, the animals received implants in the area with two different microstructures (SA-Sandblasting + acid attack and SA-H-Sandblasting + acid attack + immersion in 0.9% sodium chloride isotonic solution). All rabbits were euthanized 90 days after implant placement. The microtomographic analysis was performed to verify the number of mineralized tissues around the implants throughout their length (%BV/TV), while the histomorphometric analysis was performed to verify the percentage of bone-implant contact around the implants throughout their length (%BIC). Results We observed no differences in the quantity for %BV/TV (DBB-SA:33.25 +/- 19.67; DBB-SA-H:35.15 +/- 22.17; DBB/BM-SA:39.71 +/- 24.21; DBB/BM-SA-H:36.40 +/- 23.07) and %BIC (DBB-SA:58.94 +/- 24.37; DBB-SA-H:52.52 +/- 24.36; DBB/BM-SA: 61.66 +/- 14.60; DBB/BM-SA-H: 64.06 +/- 23.30) between the groups assessed. Conclusions The addition of BM and the type of surface did not influence the osseointegration of implants installed in areas grafted with sintered deproteinized bovine bone at high temperatures in the late period assessed.
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