☆ 4.7 Editorial Material

Reduced BNT162b2 Messenger RNA Vaccine Response in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-Naive Nursing Home Residents

CLINICAL INFECTIOUS DISEASES (2021)

COVID-19-neutralizing antibodies predict disease severity and survival

Wilfredo F. Garcia-Beltran et al.

Summary: Severe cases of COVID-19 show increased inflammatory markers, lymphopenia, pro-inflammatory cytokines, and high antibody levels. High neutralization potency is a predictor of survival. Patient sera can neutralize different strains, indicating cross-protection from reinfection.

CELL (2021)

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Article Medicine, General & Internal

Interim Results of a Phase 1-2a Trial of Ad26.COV2.S Covid-19 Vaccine

J. Sadoff et al.

Summary: The study conducted a multicenter, placebo-controlled, phase 1-2a trial, with participants randomly assigned to receive the Ad26.COV2.S vaccine. The results showed that the safety and immunogenicity profiles of the vaccine support further development.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Correction Biochemistry & Molecular Biology

Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity (vol 184, pg 2372, 2021)

Wilfredo F. Garcia-Beltran et al.

CELL (2021)

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Article Geriatrics & Gerontology

Short-term impact of nursing home SARS-CoV-2 vaccinations on new infections, hospitalizations, and deaths

Vincent Mor et al.

Summary: This study compared the impact of early and late administration of COVID-19 vaccines in nursing homes, finding that early vaccination can effectively reduce infection rates and hospitalization/death rates.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2021)

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Article Public, Environmental & Occupational Health