4.3 Review

Bone-modifying Agents (BMAs) in Breast Cancer

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Review Oncology

Breast cancer metastasis to bone: From epithelial to mesenchymal transition to breast osteoblast-like cells

Manuel Scimeca et al.

Summary: This review highlights the latest aspects of breast cancer metastasis into the bone, including biomarkers, biological processes related to the origin of metastatic cells, the role of Breast Osteoblast-Like Cells, and the prognostic value of breast microcalcifications for bone metastatic disease. Additionally, the use of molecular imaging investigations for identifying early neoplastic lesions with high propensity to form bone metastasis in vivo is proposed.

SEMINARS IN CANCER BIOLOGY (2021)

Article Oncology

Association of Osteonecrosis of the Jaw With Zoledronic Acid Treatment for Bone Metastases in Patients With Cancer

Catherine H. Van Poznak et al.

Summary: The cumulative incidence of osteonecrosis of the jaw (ONJ) after 3 years was 2.8% in patients receiving zoledronic acid for metastatic bone disease. Cancer type, oral health, and frequency of dosing were associated with the risk of ONJ. These findings provide guidance for stratifying ONJ risk in patients with metastatic bone disease receiving zoledronic acid.

JAMA ONCOLOGY (2021)

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On the pharmacological evaluation of bisphosphonates in humans

Serge Cremers et al.

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Osteocytes and Bone Metastasis

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Tumor dormancy in bone

Vera Mayhew et al.

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Manni Wang et al.

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Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry

Yi-Hsiang Hsu et al.

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MicroRNAs in Bone Metastasis

Eric Hesse et al.

CURRENT OSTEOPOROSIS REPORTS (2019)

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Performance of FRAX in Women with Breast Cancer Initiating Aromatase Inhibitor Therapy: A Registry-Based Cohort Study

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Medication-Related Osteonecrosis of the Jaw: MASCC/ISOO/ASCO Clinical Practice Guideline

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Atypical femoral fractures from bisphosphonate in cancer patients - Review

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Clinical and translational pharmacology of drugs for the prevention and treatment of bone metastases and cancer-induced bone loss

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Emily G. Atkinson et al.

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Efficacy of an orally active small-molecule inhibitor of RANKL in bone metastasis

Yuta Nakai et al.

BONE RESEARCH (2019)

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Denosumab versus bisphosphonates for the treatment of bone metastases from solid tumors: a systematic review

Jessica Y. Matuoka et al.

EUROPEAN JOURNAL OF HEALTH ECONOMICS (2019)

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Denosumab: A Review in Postmenopausal Osteoporosis

Emma D. Deeks

DRUGS & AGING (2018)

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Screening to Prevent Osteoporotic Fractures Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

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JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2018)

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Incidence of fractures among patients with rheumatoid arthritis: a systematic review and meta-analysis

S. Jin et al.

OSTEOPOROSIS INTERNATIONAL (2018)

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Cancer Survivorship

Charles L. Shapiro

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Oncology

Bone-Modifying Agents in Early-Stage and Advanced Breast Cancer

Arielle Heeke et al.

CURRENT BREAST CANCER REPORTS (2018)

Review Endocrinology & Metabolism

Hallmarks of Bone Metastasis

Rachelle W. Johnson et al.

CALCIFIED TISSUE INTERNATIONAL (2018)

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EPIDEMIOLOGY AND POSTOPERATIVE OUTCOMES OF ATYPICAL FEMORAL FRACTURES IN OLDER ADULTS: A SYSTEMATIC REVIEW

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Wnt signaling and cellular metabolism in osteoblasts

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Effect of Vitamin D on Falls and Physical Performance

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Effect of Longer-Interval vs Standard Dosing of Zoledronic Acid on Skeletal Events in Patients With Bone Metastases A Randomized Clinical Trial

Andrew L. Himelstein et al.

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NCCN Guidelines® Insights Breast Cancer, Version 1.2017 Featured Updates to the NCCN Guidelines

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Osteoporosis management in patients with breast cancer: EMAS position statement

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MATURITAS (2017)

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Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis

Kenneth G. Saag et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Endocrinology & Metabolism

Estrogen receptors alpha and beta in bone

Aysha B. Khalid et al.

Article Medicine, General & Internal

Postmenopausal Osteoporosis

Dennis M. Black et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

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Molecular Mechanisms of Bone Metastasis: Which Targets Came from the Bench to the Bedside?

Sandra Casimiro et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

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Management of bone disease in women after breast cancer

F. Milat et al.

CLIMACTERIC (2015)

Article Endocrinology & Metabolism

Bone Health and Osteoporosis

Beatrice C. Lupsa et al.

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA (2015)

Article Medicine, General & Internal

Calcium intake and risk of fracture: systematic review

Mark J. Bolland et al.

BMJ-BRITISH MEDICAL JOURNAL (2015)

Article Medicine, General & Internal

Calcium intake and risk of fracture: systematic review

Mark J. Bolland et al.

BMJ-BRITISH MEDICAL JOURNAL (2015)

Article Endocrinology & Metabolism

Alcohol consumption and hip fracture risk

X. Zhang et al.

OSTEOPOROSIS INTERNATIONAL (2015)

Review Rheumatology

Fragility fracture: recent developments in risk assessment

Terry J. Aspray

THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE (2015)

Review Orthopedics

Cancer Treatment-Induced Bone Loss in women with breast cancer

Peyman Hadji

BONEKEY REPORTS (2015)

Review Oncology

Molecular Mechanisms of Bone Metastasis and Associated Muscle Weakness

David L. Waning et al.

CLINICAL CANCER RESEARCH (2014)

Review Public, Environmental & Occupational Health

Osteoporosis Prevention, Screening, and Treatment: A Review

Juliana M. Kling et al.

JOURNAL OF WOMENS HEALTH (2014)

Article Endocrinology & Metabolism

Aromatase Inhibitor-Associated Bone Fractures: A Case-Cohort GWAS and Functional Genomics

Mohan Liu et al.

MOLECULAR ENDOCRINOLOGY (2014)

Review Medicine, General & Internal

Prevention of Bone Metastases in Breast Cancer Patients. Therapeutic Perspectives

Philippe Beuzeboc et al.

JOURNAL OF CLINICAL MEDICINE (2014)

Article Endocrinology & Metabolism

Results of indirect and mixed treatment comparison of fracture efficacy for osteoporosis treatments: a meta-analysis

N. Freemantle et al.

OSTEOPOROSIS INTERNATIONAL (2013)

Review Oncology

Metformin and breast cancer risk: a meta-analysis and critical literature review

Nananda F. Col et al.

BREAST CANCER RESEARCH AND TREATMENT (2012)

Article Obstetrics & Gynecology

Impact of cancer therapies on ovarian reserve

Clarisa R. Gracia et al.

FERTILITY AND STERILITY (2012)

Article Public, Environmental & Occupational Health

Vitamin D Deficiency in Postmenopausal Breast Cancer Survivors

Claire F. Friedman et al.

JOURNAL OF WOMENS HEALTH (2012)

Article Endocrinology & Metabolism

A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis

S. Lekamwasam et al.

OSTEOPOROSIS INTERNATIONAL (2012)

Article Medicine, General & Internal

Adjuvant tamoxifen and exemestane in early breast cancer (TEAM): a randomised phase 3 trial

Cornelis J. H. van de Velde et al.

LANCET (2011)

Article Medicine, General & Internal

Breast-Cancer Adjuvant Therapy with Zoledronic Acid

Robert E. Coleman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Nutrition & Dietetics

Prevalence and correlates of vitamin D deficiency in US adults

Kimberly Y. Z. Forrest et al.

NUTRITION RESEARCH (2011)

Article Endocrinology & Metabolism

Mortality rates after incident non-traumatic fractures in older men and women

S. Morin et al.

OSTEOPOROSIS INTERNATIONAL (2011)

Article Oncology

Denosumab for the treatment of bone metastases in breast cancer: evidence and opinion

Guenther G. Steger et al.

Therapeutic Advances in Medical Oncology (2011)

Review Oncology

Cancer to bone: a fatal attraction

Katherine N. Weilbaecher et al.

NATURE REVIEWS CANCER (2011)

Article Oncology

Prevention of Aromatase Inhibitor-Induced Bone Loss Using Risedronate: The SABRE Trial

Catherine Van Poznak et al.

JOURNAL OF CLINICAL ONCOLOGY (2010)

Article Endocrinology & Metabolism

The potential impact of new National Osteoporosis Foundation guidance on treatment patterns

B. Dawson-Hughes et al.

OSTEOPOROSIS INTERNATIONAL (2010)

Review Endocrinology & Metabolism

Development and use of FRAXA® in osteoporosis

J. A. Kanis et al.

OSTEOPOROSIS INTERNATIONAL (2010)

Review Oncology

Breast cancer metastasis to the bone: mechanisms of bone loss

Yu-Chi Chen et al.

BREAST CANCER RESEARCH (2010)

Review Obstetrics & Gynecology

Effect of bilateral oophorectomy on women's long-term health

William H. Parker et al.

WOMENS HEALTH (2009)

Review Pharmacology & Pharmacy

Aromatase Inhibitor-Associated Bone Loss Clinical Considerations

Shubham Pant et al.

Review Medicine, General & Internal

Bisphosphonates: Mechanism of action and role in clinical practice

Mathew T. Drake et al.

MAYO CLINIC PROCEEDINGS (2008)

Article Oncology

Molecular mechanisms of action of bisphosphonates: Current status

Anke J. Roelofs et al.

CLINICAL CANCER RESEARCH (2006)

Article Endocrinology & Metabolism

Body mass index as a predictor of fracture risk:: A meta-analysis

C De Laet et al.

OSTEOPOROSIS INTERNATIONAL (2005)

Article Endocrinology & Metabolism

Smoking and fracture risk: a meta-analysis

JA Kanis et al.

OSTEOPOROSIS INTERNATIONAL (2005)

Article Endocrinology & Metabolism

A meta-analysis of previous fracture and subsequent fracture risk

JA Kanis et al.

Review Multidisciplinary Sciences

Osteoclast differentiation and activation

WJ Boyle et al.

NATURE (2003)

Article Endocrinology & Metabolism

Fracture risk after bilateral oophorectomy in elderly women

LJ Melton et al.

JOURNAL OF BONE AND MINERAL RESEARCH (2003)

Review Oncology

Osteopenia and osteoporosis in women with breast cancer

B Ramaswamy et al.

SEMINARS IN ONCOLOGY (2003)

Article Medicine, General & Internal

Clinical use of bone densitometry - Scientific review

SR Cummings et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2002)

Review Oncology

Dissemination and growth of cancer cells in metastatic sites

AF Chambers et al.

NATURE REVIEWS CANCER (2002)

Review Medicine, General & Internal

Drug therapy - Side effects of adjuvant treatment of breast cancer

CL Shapiro et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)