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Epigenetics and arterial hypertension: the challenge of emerging evidence
Simonetta Friso et al.
TRANSLATIONAL RESEARCH (2015)
Oxidative stress: a concept in redox biology and medicine
Helmut Sies
REDOX BIOLOGY (2015)
Antioxidant responses and cellular adjustments to oxidative stress
Cristina Espinosa-Diez et al.
REDOX BIOLOGY (2015)
Reactive oxygen species and mitochondria: A nexus of cellular homeostasis
Joe Dan Dunn et al.
REDOX BIOLOGY (2015)
Pathogenesis of Target Organ Damage in Hypertension: Role of Mitochondrial Oxidative Stress
Speranza Rubattu et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Transgenic Overexpression of Uncoupling Protein 2 Attenuates Salt-Induced Vascular Dysfunction by Inhibition of Oxidative Stress
Shuangtao Ma et al.
AMERICAN JOURNAL OF HYPERTENSION (2014)
Poldip2 controls vascular smooth muscle cell migration by regulating focal adhesion turnover and force polarization
Srinivasa Raju Datla et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2014)
Nox2-Induced Production of Mitochondrial Superoxide in Angiotensin II-Mediated Endothelial Oxidative Stress and Hypertension
Sergey I. Dikalov et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Oxidative Stress in Hypertension: Role of the Kidney
Magali Araujo et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Nox NADPH Oxidases and the Endoplasmic Reticulum
Francisco R. M. Laurindo et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
NADPH Oxidases in Redox Regulation of Cell Adhesion and Migration
Katrin Schroeder
ANTIOXIDANTS & REDOX SIGNALING (2014)
Endoplasmic Reticulum Stress and Nox-Mediated Reactive Oxygen Species Signaling in the Peripheral Vasculature: Potential Role in Hypertension
Celio X. C. Santos et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Brain Stem NOS and ROS in Neural Mechanisms of Hypertension
Samuel H. H. Chan et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Free radicals, reactive oxygen species, oxidative stress and its classification
Volodymyr I. Lushchak
CHEMICO-BIOLOGICAL INTERACTIONS (2014)
eNOS Uncoupling in Cardiovascular Diseases - the Role of Oxidative Stress and Inflammation
Susanne Karbach et al.
CURRENT PHARMACEUTICAL DESIGN (2014)
Nox family NADPH oxidases: Molecular mechanisms of activation
Ralf P. Brandes et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Caveolin-1 is a negative regulator of NADPH oxidase-derived reactive oxygen species
Feng Chen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
DC isoketal-modified proteins activate T cells and promote hypertension
Annet Kirabo et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Oxidative stress in patients affected by primary aldosteronism
Luigi Petramala et al.
JOURNAL OF HYPERTENSION (2014)
Targets of protein carbonylation in spontaneously hypertensive obese Koletsky rats and healthy Wistar counterparts: A potential role on metabolic disorders
Lucia Mendez et al.
JOURNAL OF PROTEOMICS (2014)
Nephropathy and Elevated BP in Mice with Podocyte-Specific NADPH Oxidase 5 Expression
Chet E. Holterman et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2014)
Upregulation of Intermediate-Conductance Ca2+-Activated K+ Channels (KCNN4) in Porcine Coronary Smooth Muscle Requires NADPH Oxidase 5 (NOX5)
Hope K. A. Gole et al.
PLOS ONE (2014)
Stress-responsive regulation of mitochondria through the ER unfolded protein response
T. Kelly Rainbolt et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)
Reactive oxygen species at the crossroads of inflammasome and inflammation
Anantha Harijith et al.
FRONTIERS IN PHYSIOLOGY (2014)
Suppression of endoplasmic reticulum stress improves endothelium-dependent contractile responses in aorta of the spontaneously hypertensive rat
Kathryn M. Spitler et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)
Genetic mutation of recombination activating gene 1 in Dahl salt-sensitive rats attenuates hypertension and renal damage
David L. Mattson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2013)
S-Nitrosothiols and the S-Nitrosoproteome of the Cardiovascular System
Bradley A. Maron et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Superoxide Dismutase Mimetic, MnTE-2-PyP, Attenuates Chronic Hypoxia-Induced Pulmonary Hypertension, Pulmonary Vascular Remodeling, and Activation of the NALP3 Inflammasome
Leah R. Villegas et al.
ANTIOXIDANTS & REDOX SIGNALING (2013)
Carbonyl stress induces hypertension and cardio-renal vascular injury in Dahl salt-sensitive rats
Xianguang Chen et al.
HYPERTENSION RESEARCH (2013)
A Pivotal Role for Tryptophan 447 in Enzymatic Coupling of Human Endothelial Nitric Oxide Synthase (eNOS) EFFECTS ON TETRAHYDROBIOPTERIN-DEPENDENT CATALYSIS AND eNOS DIMERIZATION
Matthew A. Benson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The A930G Polymorphism of P22phox (CYBA) Gene but Not C242T Variation Is Associated with Hypertension: A Meta-Analysis
Yu-Wang Qin et al.
PLOS ONE (2013)
Redox Regulation of Mitochondrial ATP Synthase
Sheng-Bing Wang et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2013)
TRPM2 links oxidative stress to NLRP3 inflammasome activation
Zhenyu Zhong et al.
NATURE COMMUNICATIONS (2013)
Expression and functional significance of NADPH oxidase 5 (Nox5) and its splice variants in human blood vessels
Deepesh Pandey et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2012)
Oxidative stress, Noxs, and hypertension: Experimental evidence and clinical controversies
Augusto C. Montezano et al.
ANNALS OF MEDICINE (2012)
Reactive Oxygen Species and Endothelial Function - Role of Nitric Oxide Synthase Uncoupling and Nox Family Nicotinamide Adenine Dinucleotide Phosphate Oxidases
Augusto C. Montezano et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2012)
The p47phox- and NADPH oxidase organiser 1 (NOXO1)-dependent activation of NADPH oxidase 1 (NOX1) mediates endothelial nitric oxide synthase (eNOS) uncoupling and endothelial dysfunction in a streptozotocin-induced murine model of diabetes
J. Y. Youn et al.
DIABETOLOGIA (2012)
ER stress in the brain subfornical organ mediates angiotensin-dependent hypertension
Colin N. Young et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
Claudio Hetz
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Molecular regulation of NADPH oxidase 5 via the MAPK pathway
D. Pandey et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)
ROS-induced ROS release in vascular biology: redox-redox signaling
Natalya S. Zinkevich et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)
S-Glutathionylation Reshapes Our Understanding of Endothelial Nitric Oxide Synthase Uncoupling and Nitric Oxide/Reactive Oxygen Species-Mediated Signaling
Jay L. Zweier et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Superoxide Dismutases: Role in Redox Signaling, Vascular Function, and Diseases
Tohru Fukai et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling
Ulrich Foerstermann et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Novel Nox homologues in the vasculature: focusing on Nox4 and Nox5
Augusto C. Montezano et al.
CLINICAL SCIENCE (2011)
Oxidases and peroxidases in cardiovascular and lung disease: New concepts in reactive oxygen species signaling
Imad Al Ghouleh et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Differential regulation of Nox1, Nox2 and Nox4 in vascular smooth muscle cells from WKY and SHR
Ana M. Briones et al.
JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION (2011)
Age-related changes in an antioxidant defense system in elderly patients with essential hypertension compared with healthy controls
Joanna Rybka et al.
REDOX REPORT (2011)
Orchestrating Redox Signaling Networks through Regulatory Cysteine Switches
Candice E. Paulsen et al.
ACS CHEMICAL BIOLOGY (2010)
Effects of Sepiapterin Supplementation and NOS Inhibition on Glucocorticoid-Induced Hypertension
Mya Thida et al.
AMERICAN JOURNAL OF HYPERTENSION (2010)
Mitochondria-produced superoxide mediates angiotensin II-induced inhibition of neuronal potassium current
Jing-Xiang Yin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)
Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling
Anna E. Dikalova et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)
Lymphocyte responses exacerbate angiotensin II-dependent hypertension
Steven D. Crowley et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2010)
Redox signaling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species
Andreas Daiber
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2010)
Effects of Chronic Treatment with Honokiol in Spontaneously Hypertensive Rats
Gen-Shui Zhang et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2010)
Proteomic Profiling of Perturbed Protein Sulfenation in Renal Medulla of the Spontaneously Hypertensive Rat
Raymond Tyther et al.
JOURNAL OF PROTEOME RESEARCH (2010)
Catalase overexpression prevents hypertension and tubular apoptosis in angiotensinogen transgenic mice
Nicolas Godin et al.
KIDNEY INTERNATIONAL (2010)
Antioxidants in Hypertension and Cardiovascular Disease
Ernesto L. Schiffrin
MOLECULAR INTERVENTIONS (2010)
Nox isoforms in vascular pathophysiology: insights from transgenic and knockout mouse models
Jennifer Rivera et al.
REDOX REPORT (2010)
Nitric oxide metabolites and oxidative stress in mild essential hypertension
G. Caimi et al.
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION (2010)
Antioxidant Treatment With Tempol and Apocynin Prevents Endothelial Dysfunction and Development of Renovascular Hypertension
Cristiane A. Costa et al.
AMERICAN JOURNAL OF HYPERTENSION (2009)
Antioxidant SOD Mimetic Prevents NADPH Oxidase-Induced Oxidative Stress and Renal Damage in the Early Stage of Experimental Diabetes and Hypertension
Elisa B. M. I. Peixoto et al.
AMERICAN JOURNAL OF NEPHROLOGY (2009)
SOD1 deficiency causes salt sensitivity and aggravates hypertension in hydronephrosis
Mattias Carlstrom et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)
NADPH Oxidases: Molecular Understanding Finally Reaching the Clinical Level?
Tomasz J. Guzik et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase
Celio X. C. Santos et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Targeting and Regulation of Reactive Oxygen Species Generation by Nox Family NADPH Oxidases
Thomas L. Leto et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Compartmentalization of Redox Signaling Through NADPH Oxidase-Derived ROS
Masuko Ushio-Fukai
ANTIOXIDANTS & REDOX SIGNALING (2009)
Molecular mechanisms of hypertension: role of Nox family NADPH oxidases
Mona Sedeek et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2009)
Hydrogen peroxide down-regulates inositol 1,4,5-trisphosphate receptor content through proteasome activation
A. Martin-Garrido et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Novel p47phox-Related Organizers Regulate Localized NADPH Oxidase 1 (Nox1) Activity
Davide Gianni et al.
SCIENCE SIGNALING (2009)
Oxidant and redox signaling in vascular oxygen sensing: Implications for systemic and pulmonary hypertension
Sachin A. Gupte et al.
ANTIOXIDANTS & REDOX SIGNALING (2008)
Redox signaling, vascular function, and hypertension
Moo Yeol Lee et al.
ANTIOXIDANTS & REDOX SIGNALING (2008)
NADPH oxidase CYBA polymorphisms, oxidative stress and cardiovascular diseases
Gorka San Jose et al.
CLINICAL SCIENCE (2008)
Differential vascular functions of Nox family NADPH oxidases
Ralf P. Brandes et al.
CURRENT OPINION IN LIPIDOLOGY (2008)
Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production
Sergey I. Dikalov et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Renal redox-sensitive signaling, but not blood pressure, is attenuated by Nox1 knockout in angiotensin II-dependent chronic hypertension
Alvaro Yogi et al.
HYPERTENSION (2008)
Role of the T cell in the genesis of angiotensin II-induced hypertension and vascular dysfunction
Tomasz J. Guzik et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Cysteine redox sensor in PKGIα enables oxidant-induced activation
Joseph R. Burgoyne et al.
SCIENCE (2007)
Novel mechanism of activation of NADPH oxidase 5 - Calcium sensitization via phosphorylation
Davin Jagnandan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A genome-wide search for linkage to renal function phenotypes in West Africans with type 2 diabetes
Guanjie Chen et al.
AMERICAN JOURNAL OF KIDNEY DISEASES (2007)
NOX5 variants are functionally active in endothelial cells
Rachida S. BelAiba et al.
FREE RADICAL BIOLOGY AND MEDICINE (2007)
Inadequate cytoplasmic antioxidant enzymes response contributes to the oxidative stress in human hypertension
Felipe J. Chaves et al.
AMERICAN JOURNAL OF HYPERTENSION (2007)
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
Karen Bedard et al.
PHYSIOLOGICAL REVIEWS (2007)
Free radicals and antioxidants in normal physiological functions and human disease
Marian Valko et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
Insulin-induced vascular endothelial growth factor expression is mediated by the NADPH oxidase NOX3
Stephanie Carnesecchi et al.
EXPERIMENTAL CELL RESEARCH (2006)
Modulation of vascular smooth muscle signaling by reactive oxygen species
Alicia N. Lyle et al.
PHYSIOLOGY (2006)
Redox signaling in hypertension
Tamara M. Paravicini et al.
CARDIOVASCULAR RESEARCH (2006)
Atorvastatin-induced cardioprotection is mediated by increasing inducible nitric oxide synthase and consequent S-nitrosylation of cyclooxygenase-2
S Atar et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Targeting reactive oxygen species in hypertension
ME Cifuentes et al.
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION (2006)
Byproducts of oxidative protein damage and antioxidant enzyme activities in plasma of patients with different degrees of essential hypertension
DV Simic et al.
JOURNAL OF HUMAN HYPERTENSION (2006)
Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes
QA Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Different antioxidants status, total antioxidant power and free radicals in essential hypertension
MK Kashyap et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2005)
Sympathoexcitation by central ANG II:: Roles for AT1 receptor upregulation and NAD(P)H oxidase in RVLM
L Gao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)
Superoxide mediates angiotensin II-induced influx of extracellular calcium in neural cells
MC Zimmerman et al.
HYPERTENSION (2005)
Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins
TJ Guzik et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
NOX3, a superoxide-generating NADPH oxidase of the inner ear
B Bánfi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A key role for TRPM7 channels in anoxic neuronal death
M Aarts et al.
CELL (2003)
Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases
R Takeya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension
U Landmesser et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Renal and vascular oxidative stress and salt-sensitivity of arterial pressure
RD Manning et al.
ACTA PHYSIOLOGICA SCANDINAVICA (2003)
Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals
Y Higashi et al.
AMERICAN JOURNAL OF HYPERTENSION (2002)
A Ca2+-activated NADPH oxidase in testis, spleen, and lymph nodes
B Bánfi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR
X Chen et al.
HYPERTENSION (2001)
Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: role of phospholipase D-dependent NAD(P)H oxidase-sensitive pathways
RM Touyz et al.
JOURNAL OF HYPERTENSION (2001)
Homologs of gp91phox:: cloning and tissue expression of Nox3, Nox4, and Nox5
GJ Cheng et al.
GENE (2001)
Simultaneous activation of NADPH oxidase-related proton and electron currents in human neutrophils
TE DeCoursey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
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