期刊
CHINESE CHEMICAL LETTERS
卷 32, 期 4, 页码 1541-1544出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2020.10.047
关键词
GSH sensing; Photoinduced electron transfer; Fluorescent sensor; Cancer cells imaging
资金
- National Nature Science Foundation of China [21762028, 21462027]
- Nature Science Foundation of Jiangxi Province of China [20172BCB22007]
An efficient PET probe has been developed, capable of being activated by GSH and distinguishing cancer cells from normal cells.
An efficient PET-based probe, in which the ferrocene quencher and the naphthalimide fluorophore are linked by a disulfide bond, has been developed. This probe can be activated by GSH with fluorescence a turn-on response for blocking the PET process. In addition, it was successfully applied for distinguishing cancer cells from normal cells (c) 2020 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
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