期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 27, 期 39, 页码 10186-10192出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.202101086
关键词
aggregation induced emission; biosensors; sequence-defined oligomers; solid phase polymer; supramolecular synthesis
资金
- DFG through the collaborative research center 1093
- Projekt DEAL
The use of AIE luminophore for conjugation onto supramolecular ligands enables the detection of ligand binding. The positioning of the luminophore within the ligand scaffold strongly affects the AIE properties. Studies demonstrate that the position within the ligand structure significantly influences the performance of AIE.
A luminophore with aggregation-induced emission (AIE) is employed for the conjugation onto supramolecular ligands to allow for detection of ligand binding. Supramolecular ligands are based on the combination of sequence-defined oligo(amidoamine) scaffolds and guanidiniocarbonyl-pyrrole (GCP) as binding motif. We hypothesize that AIE properties are strongly affected by positioning of the luminophore within the ligand scaffold. Therefore, we systematically investigate the effects placing the AIE luminophore at different positions within the overall construct, for example, in the main or side chain of the olig(amidoamine). Indeed, we can show that the position within the ligand structure strongly affects AIE, both for the ligand itself as well as when applying the ligand for the detection of different biological and synthetic polyanions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据