期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 27, 期 28, 页码 7646-7650出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.202100368
关键词
Artificial phosphatases; homogeneous catalysis; Ag-SR coordination polymers; self-assembly; supramolecular chemistry
资金
- Fujian Provincial Department of Science and Technology [2020Y0038]
- Xiamen Municipal Bureau of Science and Technology [3502Z20193029]
Adding Ag+ and Zn2+ ions to thiols can lead to the formation of multivalent metal coordination polymers with high reactivity, capable of catalyzing the transphosphorylation of an RNA-model compound. It was demonstrated that the catalytic activity could be modulated by changing the length of the hydrophobic alkyl chain.
We show herein the phosphatase-like catalytic activity of coordination polymers obtained after adding Ag+-ions to thiols bearing hydrophobic alkyl chains terminated with a 1,4,7-triazacyclononane (TACN) group. The subsequent addition of Zn2+ -ions to the self-assembled polymers resulted in the formation of multivalent metal coordination polymers capable of catalysing the transphosphorylation of an RNA-model compound (2-hydroxypropyl-4-nitrophenyl phosphate, HPNPP) with high reactivity. Analysis of a series of metal ions showed that the highest catalytic activity was obtained when Ag+-ions were used as the first metal ions to construct the backbone of the coordination polymer through interaction with the -SH group followed by Zn2+-ions as the second metal ions complexed by the TACN-macrocycle. Furthermore, it was demonstrated that the catalytic activity could be modulated by changing the length of the hydrophobic alkyl chain.
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