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Elena B. M. Breidenstein et al.
TRENDS IN MICROBIOLOGY (2011)
TonB-Dependent Transporters: Regulation, Structure, and Function
Nicholas Noinaj et al.
ANNUAL REVIEW OF MICROBIOLOGY, VOL 64, 2010 (2010)
Outbreak of Meropenem-Resistant Serratia marcescens Comediated by Chromosomal AmpC β-Lactamase Overproduction and Outer Membrane Protein Loss
Borum Suh et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Kinetic Parameters of Efflux of Penicillins by the Multidrug Efflux Transporter AcrAB-TolC of Escherichia coli
Siew Ping Lim et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Porins in prokaryotes and eukaryotes: common themes and variations
Kornelius Zeth et al.
BIOCHEMICAL JOURNAL (2010)
Toward Screening for Antibiotics with Enhanced Permeation Properties through Bacterial Porins
Eric Hajjar et al.
BIOCHEMISTRY (2010)
Bridging Timescales and Length Scales: From Macroscopic Flux to the Molecular Mechanism of Antibiotic Diffusion through Porins
Eric Hajjar et al.
BIOPHYSICAL JOURNAL (2010)
Comparing the Temperature-Dependent Conductance of the Two Structurally Similar E. coli Porins OmpC and OmpF
Istvan Biro et al.
BIOPHYSICAL JOURNAL (2010)
Down-regulation of porin M35 in Moraxella catarrhalis by aminopenicillins and environmental factors and its potential contribution to the mechanism of resistance to aminopenicillins
Marion Jetter et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2010)
Implication of Porins in β-Lactam Resistance of Providencia stuartii
Que-Tien Tran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Oncocin (VDKPPYLPRPRPPRRIYNR-NH2): A Novel Antibacterial Peptide Optimized against Gram-Negative Human Pathogens
Daniel Knappe et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Cation-selective Pathway of OmpF Porin Revealed by Anomalous X-ray Diffraction
Balasundaresan Dhakshnamoorthy et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Ion Selectivity of α-Hemolysin with β-Cyclodextrin Adapter. II. Multi-Ion Effects Studied with Grand Canonical Monte Carlo/Brownian Dynamics Simulations
Bernhard Egwolf et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2010)
Molecular Basis of Enrofloxacin Translocation through OmpF, an Outer Membrane Channel of Escherichia coli - When Binding Does Not Imply Translocation
Kozhinjampara R. Mahendran et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2010)
Molecular Simulations Reveal the Mechanism and the Determinants for Ampicillin Trans location through OmpF
Amit Kumar et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2010)
Current Status of the AMOEBA Polarizable Force Field
Jay W. Ponder et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2010)
Structural and dynamical properties of the porins OmpF and OmpC: insights from molecular simulations
Amit Kumar et al.
JOURNAL OF PHYSICS-CONDENSED MATTER (2010)
Synchrotron UV Fluorescence Microscopy Uncovers New Probes in Cells and Tissues
Frederic Jamme et al.
MICROSCOPY AND MICROANALYSIS (2010)
The Crystal Structure of OprG from Pseudomonas aeruginosa, a Potential Channel for Transport of Hydrophobic Molecules across the Outer Membrane
Debra S. Touw et al.
PLOS ONE (2010)
Directed epitope delivery across the Escherichia coli outer membrane through the porin OmpF
Nicholas G. Housden et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB
Mikio Tanabe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Permeation of Antibiotics through Escherichia coli OmpF and OmpC Porins: Screening for Influx on a Single-Molecule Level
Kozhinjampara R. Mahendran et al.
JOURNAL OF BIOMOLECULAR SCREENING (2010)
Development of a liquid chromatography/mass spectrometry-based drug accumulation assay in Pseudomonas aeruginosa
Hongliang Cai et al.
ANALYTICAL BIOCHEMISTRY (2009)
Multidrug Resistance in Bacteria
Hiroshi Nikaido
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Rapid and Reliable Detection of Antimicrobial Peptide Penetration into Gram-Negative Bacteria Based on Fluorescence Quenching
Monica Benincasa et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Understanding Ion Conductance on a Molecular Level: An All-Atom Modeling of the Bacterial Porin OmpF
Soroosh Pezeshki et al.
BIOPHYSICAL JOURNAL (2009)
Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America
Helen W. Boucher et al.
CLINICAL INFECTIOUS DISEASES (2009)
The natural history of antibiotics
Jon Clardy et al.
CURRENT BIOLOGY (2009)
Combination of IMP-4 metallo-β-lactamase production and porin deficiency causes carbapenem resistance in a Klebsiella oxytoca clinical isolate
Li-rong Chen et al.
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE (2009)
Antibiotic translocation through membrane channels: temperature-dependent ion current fluctuation for catching the fast events
Kozhinjampara R. Mahendran et al.
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2009)
The Glycerol-3-Phosphate Permease GlpT Is the Only Fosfomycin Transporter in Pseudomonas aeruginosa
Alfredo Castaneda-Garcia et al.
JOURNAL OF BACTERIOLOGY (2009)
Relationship between the expression of ompF and quinolone resistance in Escherichia coli
Ryuta Kishii et al.
JOURNAL OF INFECTION AND CHEMOTHERAPY (2009)
Reduced susceptibility to carbapenems in Klebsiella pneumoniae clinical isolates associated with plasmid-mediated beta-lactamase production and OmpK36 porin deficiency
Xuan Ding Wang et al.
JOURNAL OF MEDICAL MICROBIOLOGY (2009)
NanC Crystal Structure, a Model for Outer-Membrane Channels of the Acidic Sugar-Specific KdgM Porin Family
Christophe Wirth et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Transmembrane passage of hydrophobic compounds through a protein channel wall
Elizabeth M. Hearn et al.
NATURE (2009)
How β-Lactam Antibiotics Enter Bacteria: A Dialogue with the Porins
Chloe E. James et al.
PLOS ONE (2009)
Mechanisms of carbapenem resistance in non-metallo-β-lactamase-producing clinical isolates of Pseudomonas aeruginosa from a Tunisian hospital
S. Hammami et al.
PATHOLOGIE BIOLOGIE (2009)
Simulations of anion transport through OprP reveal the molecular basis for high affinity and selectivity for phosphate
Prapasiri Pongprayoon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Kinetic behavior of the major multidrug efflux pump AcrB of Escherichia coli
Keiji Nagano et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Extended-spectrum beta-lactamases and the permeability barrier
L. Martinez-Martinez
CLINICAL MICROBIOLOGY AND INFECTION (2008)
Crystal structures of the OmpF porin: function in a colicin translocon
Eiki Yamashita et al.
EMBO JOURNAL (2008)
Emergence of imipenem resistance in clinical Escherichia coli during therapy
Jesus Oteo et al.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2008)
Federal funding for the study of antimicrobial resistance in nosocomial pathogens: No ESKAPE
Louis B. Rice
JOURNAL OF INFECTIOUS DISEASES (2008)
Physicochemical properties of antibacterial compounds: Implications for drug discovery
Rosemarie O'Shea et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Facilitated permeation of antibiotics across membrane channels - Interaction of the quinolone moxifloxacin with the OmpF channel
Tivadar Mach et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria
Jean-Marie Pages et al.
NATURE REVIEWS MICROBIOLOGY (2008)
Outer membrane protein G: Engineering a quiet pore for biosensing
Min Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Crystal structure of the outer membrane protein OpdK from Pseudomonas aeruginosa
Shyamasri Biswas et al.
STRUCTURE (2008)
Structural insight into OprD substrate specificity
Shyamasri Biswas et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Collateral damage of flomoxef therapy:: in vivo development of porin deficiency and acquisition of blaDHA-1 leading to ertapenem resistance in a clinical isolate of Klebsiella pneumoniae producing CTX-M-3 and SHV-5 β-lactamases
Chen-Hsiang Lee et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2007)
Intracellular accumulation of linezolid in Escherichia coli, Citrobacter freundii and Enterobacter aerogenes:: role of enhanced efflux pump activity and inactivation
Anja Schumacher et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2007)
Drugs for bad bugs: confronting the challenges of antibacterial discovery
David J. Payne et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
An arginine ladder in OprP mediates phosphate-specific transfer across the outer membrane
Trevor F. Moraes et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Crystal structure of osmoporin OmpC from E-coli at 2.0 Å
Arnaud Basle et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
High-level carbapenem resistance in a Klebsiella pneumoniae clinical isolate is due to the combination of blaACT-1 β-lactamase production, porin OmpK35/36 insertional inactivation, and down-regulation of the phosphate transport porin PhoE
Frank M. Kaczmarek et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)
Outer membrane protein changes and efflux pump expression together may confer resistance to ertapenem in Enterobacter cloacae
Dora Szabo et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)
Molecular transport through channels and pores: Effects of in-channel interactions and blocking
Wolfgang R. Bauer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Crystal structure of the monomeric porin OmpG
Gowtham V. Subbarao et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Multidrug resistance pump AcrAB-TolC is required for high-level, Tet(A)-mediated tetracycline resistance in Escherichia coli
Ricardo E. de Cristobal et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2006)
Interplay of efflux system, ampC, and oprD expression in carbapenem resistance of Pseudomonas aeruginosa clinical isolates
J Quale et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2006)
The outer membrane protein OmpW forms an eight-stranded β-barrel with a hydrophobic channel
HD Hong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Interaction of zwitterionic penicillins with the OmpF channel facilitates their translocation
C Danelon et al.
BIOPHYSICAL JOURNAL (2006)
Role of the novel OprD family of porins in nutrient uptake in Pseudomonas aeruginosa
S Tamber et al.
JOURNAL OF BACTERIOLOGY (2006)
Identification of an OprD homologue in Acinetobacter baumannii
M Dupont et al.
JOURNAL OF PROTEOME RESEARCH (2005)
Imaging α-hemolysin with molecular dynamics:: Ionic conductance, osmotic permeability, and the electrostatic potential map
A Aksimentiev et al.
BIOPHYSICAL JOURNAL (2005)
Acquisition of resistance to carbapenems in multidrug-resistant clinical strains of Acinetobacter baumannii:: Natural Insertional inactivation of a gene encoding a member of a novel family of β-barrel outer membrane proteins
MA Mussi et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2005)
Theoretical and computational models of biological ion channels
B Roux et al.
QUARTERLY REVIEWS OF BIOPHYSICS (2004)
Crystal structure of the bacterial nucleoside transporter Tsx
JQ Ye et al.
EMBO JOURNAL (2004)
Role of β-lactamases and porins in resistance to ertapenem and other β-lactams in Klebsiella pneumoniae
GA Jacoby et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)
Subconductance states in OmpF gating
A Baslé et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2004)
Microscopic mechanism of antibiotics translocation through a porin
M Ceccarelli et al.
BIOPHYSICAL JOURNAL (2004)
Resistance to imipenem, cefepime, and cefpirome associated with mutation in Omp36 osmoporin of Enterobacter aerogenes
A Thiolas et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Ion permeation through the α-hemolysin channel:: Theoretical studies based on Brownian dynamics and Poisson-Nernst-Plank electrodiffusion theory
SY Noskov et al.
BIOPHYSICAL JOURNAL (2004)
Electroosmotic enhancement of the binding of a neutral molecule to a transmembrane pore
LQ Gu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Accumulation of garenoxacin by Bacteroides fragilis compared with that of five fluoroquinolones
V Ricci et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2003)
Role of Klebsiella pneumoniae OmpK35 porin in antimicrobial resistance
A Doménech-Sánchez et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
Imipenem resistance in Salmonella enterica serovar Wien related to porin loss and CMY-4 β-lactamase production
L Armand-Lefèvre et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
Resistance to β-lactams among blood isolates of Salmonella spp. in European hospitals:: results from the SENTRY Antimicrobial Surveillance Program 1997-98
LS Tzouvelekis et al.
CLINICAL MICROBIOLOGY AND INFECTION (2003)
Outer membrane protein alterations and bla(TEM-1) variants: their role in beta-lactam resistance in Klebsiella pneumoniae
EC Nelson et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2003)
Genes for chlorogenate and hydroxycinnamate catabolism (hca) are linked to functionally related genes in the dca-pca-qui-pob-hca chromosomal cluster of Acinetobacter sp strain ADP1
MA Smith et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2003)
Molecular basis of bacterial outer membrane permeability revisited
H Nikaido
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2003)
Carbapenem resistance in a clinical isolate of Enterobacter aerogenes is associated with decreased expression of OmpF and OmpC porin analogs
H Yigit et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
Expression of SHV-2 β-lactamase and of reduced amounts of OmpK36 porin in Klebsiella pneumoniae results in increased resistance to cephalosporins and carbapenems
B Crowley et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
Escaping free-energy minima
A Laio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Ion permeation and selectivity of OmpF porin: A theoretical study based on molecular dynamics, brownian dynamics, and continuum electrodiffusion theory
W Im et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Identification and analysis of amino acid mutations in porin IB that mediate intermediate-level resistance to penicillin and tetracycline in Neisseria gonorrhoeae
M Olesky et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
Method for estimation of low outer membrane permeability to β-lactam antibiotics
B Lakaye et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
DNA gyrase and topoisomerase IV mutations associated with fluoroquinolone resistance in Proteus mirabilis
LM Weigel et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
Designed to penetrate: Time-resolved interaction of single antibiotic molecules with bacterial pores
EM Nestorovich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Ions and counterions in a biological channel:: A molecular dynamics simulation of OmpF porin from Escherichia coli in an explicit membrane with 1 M KCl aqueous salt solution
W Im et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
The benPK operon, proposed to play a role in transport, is part of a regulon for benzoate catabolism in Acinetobacter sp strain ADP1
TJ Clark et al.
MICROBIOLOGY-SGM (2002)
Transport of maltodextrins through maltoporin: A single-channel study
L Kullman et al.
BIOPHYSICAL JOURNAL (2002)
Cloning and sequencing of Enterobacter aerogenes OmpC-type osmoporin linked to carbapenem resistance
E Sturenburg et al.
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2002)
Protected environments allow parallel evolution of a bacterial pathogen in a patient subjected to long-term antibiotic therapy
AS Low et al.
MOLECULAR MICROBIOLOGY (2001)
Calculating free energies using average force
E Darve et al.
JOURNAL OF CHEMICAL PHYSICS (2001)
Brownian dynamics simulations of ions channels: A general treatment of electrostatic reaction fields for molecular pores of arbitrary geometry
W Im et al.
JOURNAL OF CHEMICAL PHYSICS (2001)
Facilitated substrate transport through membrane proteins
C Hilty et al.
PHYSICAL REVIEW LETTERS (2001)
Genetic characterization of highly fluoroquinolone-resistant clinical Escherichia coli strains from China:: Role of acrR mutations
H Wang et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2001)
Steered molecular dynamics and mechanical functions of proteins
B Isralewitz et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2001)
Structure of outer membrane protein A transmembrane domain by NMR spectroscopy
A Arora et al.
NATURE STRUCTURAL BIOLOGY (2001)
Crystal structure of Omp32, the anion-selective porin from Comamonas acidovorans, in complex with a periplasmic peptide at 2.1 Å resolution
K Zeth et al.
STRUCTURE (2000)
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen
CK Stover et al.
NATURE (2000)
A Grand Canonical Monte Carlo-Brownian dynamics algorithm for simulating ion channels
W Im et al.
BIOPHYSICAL JOURNAL (2000)
Extended sugar slide function for the periplasmic coiled coil domain of ScrY
F Dumas et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
High-resolution structure of the OmpA membrane domain
A Pautsch et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Substitutions in the eyelet region disrupt cefepime diffusion through the Escherichia coli OmpF channel
V Simonet et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2000)
Accumulation of norfloxacin by Bacteroides fragilis
V Ricci et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2000)