Recent Advances in Paired Electrosynthesis

Progress in electroorganic synthesis is linked to innovation of new synthetic reactions with impact on medicinal chemistry and drug discovery and to the desire to minimise waste and to provide energy-efficient chemical transformations for future industrial processes. Paired electrosynthetic processes that combine the use of both anode and cathode (convergent or divergent) with minimal (or without) intentionally added electrolyte or need for additional reagents are of growing interest. In this overview, recent progress in developing paired electrolytic reactions is surveyed. The discussion focuses on electrosynthesis technology with proven synthetic value for the preparation of small molecules. Reactor types are contrasted and the concept of translating light-energy driven photoredox reactions into paired electrolytic reactions is highlighted as a newly emerging trend.

Automated summary

Progress in electroorganic synthesis is closely tied to innovation in new synthetic reactions with implications for medicinal chemistry and drug discovery, as well as the desire to reduce waste and provide energy-efficient chemical transformations for future industrial processes. Researchers have been exploring paired electrosynthetic processes that combine the use of both anode and cathode, with minimal or no intentionally added electrolyte or need for extra reagents. The concept of translating light-energy driven photoredox reactions into paired electrolytic reactions is highlighted as an emerging trend in the field.