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SCIENCE (2013)
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Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis
Hyungjin Kim et al.
MOLECULAR CELL (2009)
The murine cytomegalovirus cell death suppressor m38.5 binds Bax and blocks Bax-mediated mitochondrial outer membrane permeabilization
Damien Arnoult et al.
APOPTOSIS (2008)
Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells
Mohammad R. Abedini et al.
CANCER RESEARCH (2008)
TNF-α induces two distinct caspase-8 activation pathways
Lai Wang et al.
CELL (2008)
Cytomegalovirus m45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1
Jason W. Upton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Murine cytornegalovirus m38.5 protein inhibits Bax-mediated cell death
Igor Jurak et al.
JOURNAL OF VIROLOGY (2008)
Cytomegalovirus proteins vMIA and m38.5 link mitochondrial morphogenesis to Bcl-2 family proteins
Kristi L. Norris et al.
JOURNAL OF VIROLOGY (2008)
The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors
Yelena L. Pobezinskaya et al.
NATURE IMMUNOLOGY (2008)
Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses
Maria A. Ermolaeva et al.
NATURE IMMUNOLOGY (2008)
Both cIAP1 and cIAP2 regulate TNFα-mediated NF-κB activation
D. J. Mahoney et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Inhibition of proinflarnmatory and innate immune signaling pathways by a cytomegalovirus RIP1-interacting protein
Claudia Mack et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain
Shanshan Feng et al.
CELLULAR SIGNALLING (2007)
Cathepsin-cleaved Bid promotes apoptosis in human neutrophils via oxidative stress-induced lysosomal membrane permeabilization
Robert Blomgran et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Ubiquitination of RIP1 regulates an NF-κB independent cell-death switch in TNF signaling
Marie Anne O'Donnell et al.
CURRENT BIOLOGY (2007)
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
Thirumala-Devi Kanneganti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Role of Bax and Bak in mitochondrial morphogenesis
Mariusz Karbowski et al.
NATURE (2006)
The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
Michael Carty et al.
NATURE IMMUNOLOGY (2006)
Truncated RIP3 (tRIP3) acts upstream of FADD to induce apoptosis in the human hepatocellular carcinoma cell line QGY-7703
Shanshan Feng et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Ubiquitination of RIP is required for tumor necrosis factor α-induced NF-κB activation
HX Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1
LX Zheng et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
TD Kanneganti et al.
NATURE (2006)
Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis
F Winau et al.
IMMUNITY (2006)
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
A Degterev et al.
NATURE CHEMICAL BIOLOGY (2005)
Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-κB activation
A Dohrman et al.
JOURNAL OF IMMUNOLOGY (2005)
Interaction between phosphatidylserine and the phosphatidylserine receptor inhibits immune responses in vivo
PR Hoffmann et al.
JOURNAL OF IMMUNOLOGY (2005)
Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD
T Vanden Berghe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria
D Arnoult et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB
TR Brummelkamp et al.
NATURE (2003)
CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members
E Trompouki et al.
NATURE (2003)
Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis
UE Schaible et al.
NATURE MEDICINE (2003)
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
O Micheau et al.
CELL (2003)
Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis
QH Yang et al.
GENES & DEVELOPMENT (2003)
Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation
D Nijhawan et al.
GENES & DEVELOPMENT (2003)
Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors
VR Sutton et al.
IMMUNITY (2003)
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
T Kuwana et al.
CELL (2002)
Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves bid cleavage
JJ Reiners et al.
CELL DEATH AND DIFFERENTIATION (2002)
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
A Letai et al.
CANCER CELL (2002)
Lysosomes and the plasma membrane: trypanosomes reveal a secret relationship
NW Andrews
JOURNAL OF CELL BIOLOGY (2002)
Calpain-mediated bid cleavage and calpain-independent Bak modulation: Two separate pathways in cisplatin-induced apoptosis
A Mandic et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Identification of Omi/HtrA-2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
R Hegde et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif
LM Martins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins
AM Verhagen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8.
FC Kischkel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Resistance to tumor necrosis factor-induced cell death mediated by PMCA4 deficiency
K Ono et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Caspase-10 is an initiator caspase in death receptor signaling
L Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-κB activation and protection from cell death
K Tada et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
Y Suzuki et al.
MOLECULAR CELL (2001)
BCL-2, BCL-XL sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
EHYA Cheng et al.
MOLECULAR CELL (2001)
Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion
M Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Plasma membrane repair is mediated by Ca2+-regulated exocytosis of lysosomes
A Reddy et al.
CELL (2001)
Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways
A Suliman et al.
ONCOGENE (2001)
Structural basis of caspase-7 inhibition by XIAP
JJ Chai et al.
CELL (2001)
Recruitment, activation and retention of caspases-9 and-3 by Apaf-1 apoptosome and associated XIAP complexes
SB Bratton et al.
EMBO JOURNAL (2001)
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
SM Srinivasula et al.
NATURE (2001)
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
ZH Liu et al.
NATURE (2000)
Structural basis of IAP recognition by Smac/DIABLO
G Wu et al.
NATURE (2000)
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
N Holler et al.
NATURE IMMUNOLOGY (2000)
Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members Bid and Bax
JA Heibein et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Initiation of apoptosis by granzyme B requires direct cleavage of Bid, but not direct granzyme B-mediated caspase activation
VR Sutton et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Failure to regulate TNF-induced NF-κB and cell death responses in A20-deficient mice
EG Lee et al.
SCIENCE (2000)
Apaf-1 oligomerizes into biologically active ∼700-kDa and inactive ∼1.4-MDa apoptosome complexes
K Cain et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
R Eskes et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
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