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G Egger et al.
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Intratumoral T cell subset ratios and Fas ligand expression on brain tumor endothelium
JS Yu et al.
JOURNAL OF NEURO-ONCOLOGY (2003)
Sequential 5-aza-2′-deoxycytidine-depsipeptide FR901228 treatment induces apoptosis preferentially in cancer cells and facilitates their recognition by cytolytic T lymphocytes specific for NY-ESO-1
TS Weiser et al.
JOURNAL OF IMMUNOTHERAPY (2001)