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A cornucopia of research resources for the fourth rodent malaria parasite species

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BMC BIOLOGY
卷 19, 期 1, 页码 -

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BMC
DOI: 10.1186/s12915-021-01019-y

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The study of human malaria has been enhanced by the use of model systems like rodent malaria parasites. A recent paper has filled the gap in resources for Plasmodium vinckei, providing new datasets, experimental protocols, and phenotypes to propel this species into the 21st century.
The study of human malaria caused by species of Plasmodium has undoubtedly been enriched by the use of model systems, such as the rodent malaria parasites originally isolated from African thicket rats. A significant gap in the arsenal of resources of the species that make up the rodent malaria parasites has been the lack of any such tools for the fourth of the species, Plasmodium vinckei. This has recently been rectified by Abhinay Ramaprasad and colleagues, whose pivotal paper published in BMC Biology describes a cornucopia of new P. vinckei 'omics datasets, mosquito transmission experiments, transfection protocols, and virulence phenotypes, to propel this species firmly into the twenty-first century.

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