期刊
BIOTECHNOLOGY ADVANCES
卷 48, 期 -, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biotechadv.2021.107711
关键词
Bioimaging; Biomarkers; Cancer therapy; Gum polysaccharide nanocomposites; Metal nanoparticles; Photothermal therapy
资金
- Wenzhou Municipal Science and Technology Bureau [Y20190018]
- Wenzhou leading talent innovative project [RX2016004]
- Zhejiang Provincial Natural Science Foundation of China [LGF21H060010]
Gum polysaccharides, as a type of biopolymer, are highly available and non-toxic, making them an important alternative to synthetic polymers in the synthesis of metal nanostructures. These eco-friendly metal nanostructures endow gum-based biocomposites with remarkable characteristics for cancer diagnosis and therapy, such as bioimaging, radiotherapy, and phototherapy, laying the groundwork for future stimulating research.
Biopolymers are of prime importance among which gum polysaccharides hold an eminent standing owing to their high availability and non-toxic nature. Gum biopolymers offer a greener alternative to synthetic polymers and toxic chemicals in the synthesis of metal nanostructures. Metal nanostructures accessible via eco-friendly means endow astounding characteristics to gum-based biocomposites in the field of diagnosis and therapy towards cancer diseases. In this review, assorted approaches for the assembly of nanomaterials mediated by gum biopolymers are presented and their utility in cancer diagnosis and therapy, e.g., bioimaging, radiotherapy, and phototherapy, are deliberated to provide a groundwork for future stimulative research.
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