相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Protein-protein interactions as antibiotic targets: A medicinal chemistry perspective
Peter J. Cossar et al.
MEDICINAL RESEARCH REVIEWS (2020)
TAM receptors attenuate murine NK-cell responses via E3 ubiquitin ligase Cbl-b
Leilani M. Chirino et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2020)
Molecular Determinants for the Activation/Inhibition of Bak Protein by BH3 Peptides
Guillem Vila-Julia et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2020)
Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia
Juan Tang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Advances in the calculation of binding free energies
Anita de Ruiter et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2020)
Comprehensive Evaluation of Fourteen Docking Programs on Protein-Peptide Complexes
Gaoqi Weng et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2020)
Recent advances in the development of protein-protein interactions modulators: mechanisms and clinical trials
Haiying Lu et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
AutoDock CrankPep: combining folding and docking to predict protein-peptide complexes
Yuqi Zhang et al.
BIOINFORMATICS (2019)
End-Point Binding Free Energy Calculation with MM/PBSA and MM/GBSA: Strategies and Applications in Drug Design
Ercheng Wang et al.
CHEMICAL REVIEWS (2019)
Extensive benchmark of rDock as a peptide-protein docking tool
Daniel Soler et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2019)
1231PMaster checkpoint Cbl-b inhibition: Anti-tumour efficacy in a murine colorectal cancer model following siRNA-based cell therapy
K Thell et al.
ANNALS OF ONCOLOGY (2019)
farPPI: a webserver for accurate prediction of protein-ligand binding structures for small-molecule PPI inhibitors by MM/PB(GB)SA methods
Zhe Wang et al.
BIOINFORMATICS (2019)
Regulation of immune responses by E3 ubiquitin ligase Cbl-b
Rong Tang et al.
CELLULAR IMMUNOLOGY (2019)
Assessing the performance of the MM/PBSA and MM/GBSA methods. 10. Impacts of enhanced sampling and variable dielectric model on protein-protein Interactions
Ercheng Wang et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2019)
Assessing the performance of MM/PBSA and MM/GBSA methods. 9. Prediction reliability of binding affinities and binding poses for protein-peptide complexes
Gaoqi Weng et al.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2019)
Protein-peptide docking: opportunities and challenges
Maciej Ciemny et al.
DRUG DISCOVERY TODAY (2018)
High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein Protein Interaction
Haibin Zhou et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
HPEPDOCK: a web server for blind peptide-protein docking based on a hierarchical algorithm
Pei Zhou et al.
NUCLEIC ACIDS RESEARCH (2018)
Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction
Lei Wang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Peptidomimetic therapeutics: scientific approaches and opportunities
Nir Qvit et al.
DRUG DISCOVERY TODAY (2017)
Structural analysis of the TKB domain of ubiquitin ligase Cbl-b complexed with its small inhibitory peptide, Cblin
Ayako Ohno et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2016)
Cbl-b inhibitors as novel intra-cellular checkpoint inhibitors for cancer immunotherapy
Saket Agarwal et al.
CANCER RESEARCH (2016)
A systematic molecular dynamics approach to the study of peptide Keap1-Nrf2 protein-protein interaction inhibitors and its application to p62 peptides
Meng-Chen Lu et al.
MOLECULAR BIOSYSTEMS (2016)
Targeting CBLB as a potential therapeutic approach for disseminated candidiasis
Yun Xiao et al.
NATURE MEDICINE (2016)
Inhibition of CBLB protects from lethal Candida albicans sepsis
Gerald Wirnsberger et al.
NATURE MEDICINE (2016)
Small molecules, big targets: drug discovery faces the protein-protein interaction challenge
Duncan E. Scott et al.
NATURE REVIEWS DRUG DISCOVERY (2016)
Modulating protein-protein interactions: the potential of peptides
Laura Nevola et al.
CHEMICAL COMMUNICATIONS (2015)
State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors
Chunquan Sheng et al.
CHEMICAL SOCIETY REVIEWS (2015)
The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
Samuel Genheden et al.
EXPERT OPINION ON DRUG DISCOVERY (2015)
ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
James A. Maier et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
Modulation of immune cell functions by the E3 ligase Cbl-b
Christina Lutz-Nicoladoni et al.
FRONTIERS IN ONCOLOGY (2015)
Molecular Pathways: Cbl Proteins in Tumorigenesis and Antitumor Immunity-Opportunities for Cancer Treatment
Mariya S. Liyasova et al.
CLINICAL CANCER RESEARCH (2015)
E3 ubiquitin ligase Cbl-b in innate and adaptive immunity
Qingjun Liu et al.
CELL CYCLE (2014)
Small-Molecule Inhibitors of Protein-Protein Interactions: Progressing toward the Reality
Michelle R. Arkin et al.
CHEMISTRY & BIOLOGY (2014)
Investigation of the intermolecular recognition mechanism between the E3 ubiquitin ligase Keap1 and substrate based on multiple substrates analysis
Zheng-Yu Jiang et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2014)
Discovery of Potent Keap1-Nrf2 Protein-Protein Interaction Inhibitor Based on Molecular Binding Determinants Analysis
Zheng-Yu Jiang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells
Magdalena Paolino et al.
NATURE (2014)
rDock: A Fast, Versatile and Open Source Program for Docking Ligands to Proteins and Nucleic Acids
Sergio Ruiz-Carmona et al.
PLOS COMPUTATIONAL BIOLOGY (2014)
T Cell Activation Threshold Regulated by E3 Ubiquitin Ligase Cbl-b Determines Fate of Inducible Regulatory T Cells
Guilin Qiao et al.
JOURNAL OF IMMUNOLOGY (2013)
Assessing the Performance of MM/PBSA and MM/GBSA Methods. 3. The Impact of Force Fields and Ligand Charge Models
Lei Xu et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2013)
Structural basis of the interactions between CXCR4 and CXCL12/SDF-1 revealed by theoretical approaches
Lei Xu et al.
MOLECULAR BIOSYSTEMS (2013)
Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3
Hao Dou et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Peptide Truncation Leads to a Twist and an Unusual Increase in Affinity for Casitas B-Lineage Lymphoma Tyrosine Kinase Binding Domain
Eric A. Kumar et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Assessing the Performance of the MM/PBSA and MM/GBSA Methods. 1. The Accuracy of Binding Free Energy Calculations Based on Molecular Dynamics Simulations
Tingjun Hou et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2011)
Essential Role of E3 Ubiquitin Ligase Activity in Cbl-b-Regulated T Cell Functions
Magdalena Paolino et al.
JOURNAL OF IMMUNOLOGY (2011)
ZAP-70: An Essential Kinase in T-cell Signaling
Haopeng Wang et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
Spontaneous tumor rejection by cbl-b-deficient CD8+ T cells
Stefanie Loeser et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
AMBER force-field parameters for phosphorylated amino acids in different protonation states: phosphoserine, phosphothreonine, phosphotyrosine, and phosphohistidine
N Homeyer et al.
JOURNAL OF MOLECULAR MODELING (2006)
The Amber biomolecular simulation programs
DA Case et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2005)
Towards a proteome-scale map of the human protein-protein interaction network
JF Rual et al.
NATURE (2005)
Essential role of the E3 ubiquitin ligase Cbl-b in T cell anergy induction
MS Jeon et al.
IMMUNITY (2004)
A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations
Y Duan et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2003)
Molecular mechanical models for organic and biological systems going beyond the atom centered two body additive approximation: Aqueous solution free energies of methanol and N-methyl acetamide, nucleic acid base, and amide hydrogen bonding and chloroform/water partition coefficients of the nucleic acid bases
P Cieplak et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2001)
Modification of the generalized Born model suitable for macromolecules
A Onufriev et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2000)
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
K Bachmaier et al.
NATURE (2000)
分享论文
