4.7 Article

N-Substituted pyrrolopyrimidines and purines as p90 ribosomal S6 protein kinase-2 (RSK2) inhibitors

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Substituted pteridinones as p90 ribosomal S6 protein kinase (RSK) inhibitors: A structure-activity study

Kimberly A. Casalvieri et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2020)

Review Oncology

Defining the role of the RSK isoforms in cancer

Thibault Houles et al.

SEMINARS IN CANCER BIOLOGY (2018)

Article Chemistry, Medicinal

Design and synthesis of potent RSK inhibitors

Rama Jain et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)

Review Oncology

Selective Targeting of RSK Isoforms in Cancer

Kimberly A. Casalvieri et al.

TRENDS IN CANCER (2017)

Article Chemistry, Medicinal

Discovery of Potent and Selective RSK Inhibitors as Biological Probes

Rama Jain et al.

JOURNAL OF MEDICINAL CHEMISTRY (2015)

Article Chemistry, Multidisciplinary

Trifluoroacetic Acid in 2,2,2-Trifluoroethanol Facilitates SNAr Reactions of Heterocycles with Arylamines

Benoit Carbain et al.

CHEMISTRY-A EUROPEAN JOURNAL (2014)

Article Biochemistry & Molecular Biology

Prediction of hydration free energies for the SAMPL4 diverse set of compounds using molecular dynamics simulations with the OPLS-AA force field

Oliver Beckstein et al.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2014)

Review Oncology

The p90 RSK Family Members: Common Functions and Isoform Specificity

Romain Lara et al.

CANCER RESEARCH (2013)

Review Biochemistry & Molecular Biology

Regulation and function of the RSK family of protein kinases

Yves Romeo et al.

BIOCHEMICAL JOURNAL (2012)

Article Pharmacology & Pharmacy

Paving the way for targeting RSK in cancer

Yves Romeo et al.

EXPERT OPINION ON THERAPEUTIC TARGETS (2011)

Article Chemistry, Medicinal

Identifying and Characterizing Binding Sites and Assessing Druggability

Thomas A. Halgren

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2009)

Review Cell Biology

The RSK family of kinases: emerging roles in cellular signalling

Rana Anjum et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

The selectivity of protein kinase inhibitors: a further update

Jenny Bain et al.

BIOCHEMICAL JOURNAL (2007)

Article Biochemistry & Molecular Biology

A clickable inhibitor reveals context-dependent autoactivation of p90 RSK

Michael S. Cohen et al.

NATURE CHEMICAL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

Gopal P. Sapkota et al.

BIOCHEMICAL JOURNAL (2007)

Article Chemistry, Medicinal

Extra precision glide: Docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes

Richard A. Friesner et al.

JOURNAL OF MEDICINAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

PHASE: a new engine for pharmacophore perception, 3D QSAR model development, and 3D database screening: 1. Methodology and preliminary results

Steven L. Dixon et al.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2006)

Article Biochemistry & Molecular Biology

PHASE: A novel approach to pharmacophore modeling and 3D database searching

Steven L. Dixon et al.

CHEMICAL BIOLOGY & DRUG DESIGN (2006)

Article Biochemistry & Molecular Biology

Functional characterization of human RSK4, a new 90-kDa ribosomal S6 kinase, reveals constitutive activation in most cell types

BA Dümmler et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Chemistry, Medicinal

Glide: A new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy

RA Friesner et al.

JOURNAL OF MEDICINAL CHEMISTRY (2004)