期刊
BIOMEDICAL MATERIALS
卷 16, 期 4, 页码 -出版社
IOP PUBLISHING LTD
DOI: 10.1088/1748-605X/abfd11
关键词
fluorescent probes; metabolites; imaging
资金
- US National Institutes of Health [GM124316, MH110975]
Advancements in fluorescent probes have enabled effective monitoring of key cellular metabolites, such as ATP, cAMP, cGMP, NADH, ROS, sugar, CO, and NO, for both whole cell and subcellular imaging.
Cellular metabolites play a crucial role in promoting and regulating cellular activities, but it has been difficult to monitor these cellular metabolites in living cells and in real time. Over the past decades, iterative development and improvements of fluorescent probes have been made, resulting in the effective monitoring of metabolites. In this review, we highlight recent progress in the use of fluorescent probes for tracking some key metabolites, such as adenosine triphosphate, cyclic adenosine monophosphate, cyclic guanosine 5'-monophosphate, Nicotinamide adenine dinucleotide (NADH), reactive oxygen species, sugar, carbon monoxide, and nitric oxide for both whole cell and subcellular imaging.
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