期刊
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
卷 555, 期 -, 页码 40-45出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.bbrc.2021.03.072
关键词
Exocytosis; Plant immunity; RIN4
资金
- National Natural Science Foundation of China [31270315]
- National Key Research and Development Program of China [2016YFD0100600]
RIN4 is an important immunomodulator in Arabidopsis, which interacts with the exocyst subunit EXO70E2 to promote extracellular export of defense-related vesicles. It is targeted by multiple pathogenic effectors and guarded by different immune receptors.
RIN4 is an important immunomodulator in Arabidopsis, which is targeted by multiple pathogenic effectors, and consequently guarded by different immune receptors. Although RIN4 plays a significant role in plant immunity, its molecular function is not fully understood. We found that RIN4 interacts with the exocyst subunit EXO70E2. Transiently expressed RIN4 can recruits EXO70E2 vesicles to the plasma membrane, and promote the transport of the vesicles to the extracellular matrix. RIN4 also can decrease the protein level of EXO70E2. Base on the fact that EXO70 proteins positively mediates plant immunity, the function of RIN4 is to promote the extracellular export of defense related vesicles. Pathogens will secret effectors to modify or cleavage it to interfere this exocytosis. 0 2021 Elsevier Inc. All rights reserved.
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