期刊
ANNUAL REVIEW OF IMMUNOLOGY, VOL 39
卷 39, 期 -, 页码 417-447出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev-immunol-101819-074948
关键词
adaptive NK cell; innate immunity; immunological memory; MCMV; mouse cytomegalovirus; HCMV; human cytomegalovirus
类别
资金
- Australia National Health and Medical Research Council Early Career Fellowship [GNT1158615]
- US National Institutes of Health [AI100874, AI130043, P30CA008748]
- Ludwig Center for Cancer Immunotherapy
- American Cancer Society
- Burroughs Wellcome Fund
NK cells play a crucial role in host defense against pathogens and cancer, known for their early and rapid effector activity and ability to undergo adaptive immune processes. NK cells exhibit flexibility in both innate and adaptive responses, showcasing their versatility in human NK cell-mediated immunity.
Natural killer (NK) cells are innate lymphocytes that provide critical host defense against pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells have been recognized over the last decade for their ability to undergo adaptive immune processes, including antigendriven clonal expansion and generation of long-lived memory. This review presents an overview of how NK cells lithely partake in both innate and adaptive responses and how this versatility is manifest in human NK cell-mediated immunity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据