☆ 4.4 Editorial Material

Introduction of the special issue, Clinical reproductive immunology

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2021)

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Article Immunology

Clinical molecular genetics evaluation in women with reproductive failures

Mahmood Y. Bilal et al.

Summary: Molecular diagnostics plays a crucial role in various medical fields, especially in reproductive medicine, aiding in the diagnosis and treatment of infertility and recurrent reproductive failures. Molecular methods such as reverse transcription polymerase chain reaction and next generation sequencing can be used to probe the factors behind these conditions.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2021)

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Article Immunology

Natural killer cells and reproductive success

Gavin Sacks et al.

Summary: NK cell assessment is a common immune test for clinicians, with better methodology such as flow cytometry potentially improving accuracy in the future. Blood testing is noninvasive and may serve as a marker for immune dysfunction, especially in cases of repeated reproductive failure. Additionally, a new genetic test (the KIR/HLA-C interaction) could provide a more effective diagnostic tool for immune therapy trials.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2021)

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Article Immunology

Intralipid treatment for women with reproductive failures

Carolyn B. Coulam

Summary: Intravenous intralipid treatment can successfully modulate abnormal NK cell activity in women with reproductive problems, and can enhance live birth rates in patients diagnosed with recurrent implantation failure or recurrent pregnancy loss.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2021)

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Article Immunology

Novel predictive and therapeutic options for better pregnancy outcome in frozen embryo transfer cycles

Warren J. Huber et al.

Summary: The advancement of IVF technology has led to an increase in multiple pregnancies, but the use of embryo freezing techniques has resulted in a gradual reduction in the number of embryos transferred, further improving pregnancy success rates.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2021)

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Article Immunology

Pelvic endometriosis and natural killer cell immunity

Atsushi Fukui et al.

Summary: Endometriosis is a common chronic disease that predominantly affects women of reproductive age. Infertility associated with endometriosis is often due to factors such as pelvic adhesions and oocyte damage. The condition can be caused by bacterial infections, immunological abnormalities, epigenetics, and aberrant DNA methylation. NK cells in the peritoneal fluid play a role in eliminating endometrial cells, but changes in their receptors and cytokine production may contribute to the development of endometriosis in affected women.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2021)

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Article Immunology

Anti-sperm antibodies and reproductive failures

Hiroaki Shibahara et al.

Summary: ASA is an immune factor that can cause infertility and miscarriage in women. Testing for ASA in infertile women and handling gametes and embryos carefully during treatment can lead to satisfactory outcomes.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2021)

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Review Immunology

Immunology's Coming of Age

Stefan H. E. Kaufmann

FRONTIERS IN IMMUNOLOGY (2019)

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Article Immunology

Current Trends of Reproductive Immunology Practices in In Vitro fertilization (IVF) - A First World Survey Using IVF-Worldwide.com

Joanne Kwak-Kim et al.

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2013)

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Editorial Material Multidisciplinary Sciences

Pregnant women deserve better

Francoise Baylis

NATURE (2010)

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