期刊
AMERICAN JOURNAL OF NEURORADIOLOGY
卷 42, 期 7, 页码 1190-1195出版社
AMER SOC NEURORADIOLOGY
DOI: 10.3174/ajnr.A7113
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This study quantitatively evaluated small neurologic events in COVID-19 patients and explored the spread of these events using a network diffusion model. The findings provide insights into the distribution and association of neurologic events in different brain regions.
BACKGROUND: Neurologic events have been reported in patients with coronavirus disease 2019 (COVID-19). However, a model-based evaluation of the spatial distribution of these events is lacking. PURPOSE: Our aim was to quantitatively evaluate whether a network diffusion model can explain the spread of small neurologic events. DATA SOURCES: The MEDLINE, EMBASE, Scopus, and LitCovid data bases were searched from January 1, 2020, to July 19, 2020. STUDY SELECTION: Thirty-five case series and case studies reported 317 small neurologic events in 123 unique patients with COVID-19. DATA ANALYSIS: Neurologic events were localized to gray or white matter regions of the Illinois Institute of Technology (gray-matter and white matter) Human Brain Atlas using radiologic images and descriptions. The total proportion of events was calculated for each region. A network diffusion model was implemented, and any brain regions showing a significant association (P?
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