A composite prepared from covalent organic framework and gold nanoparticles for the electrochemical determination of enrofloxacin

A high conductivity composite based on covalent organic frameworks/gold nanoparticles (TAPB-PDA-COFs/AuNPs, TAPB: 3,5-tris(4-aminophenyl)benzene, PDA: p-phthalaldehyde) was prepared by a simple in-situ synthesized method and a novel electrochemical sensor based on TAPB-PDA-COFs/AuNPs was constructed for detection of Enrofloxacin (ENR). A variety of different characterization techniques including ultraviolet-visible spectrophotometer (UV-vis), fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS) were used to characterize the TAPB-PDA-COFs/AuNPs. ENR was detected by square wave stripping voltammetry (SWV) according to the relationship between the ENR concentration and the oxidation peak current. The result showed that TAPB-PDA-COFs/AuNPs was synthesized successfully. The electrochemical sensor showed two linear ranges in the range of 0.05-10 mu mol L-1 and 10-120 mu mol L-1 with the limit of detection of 0.041 mu mol L-1 (S/N = 3). The good recoveries (96.7-102.2%) and low RSDs (0.9-6.4%) indicated the possibility of using this sensor for actual sample detection. Therefore, TAPB-PDA-COFs/AuNPs-based electrochemical sensor showed good performance in detecting ENR, and would be a potential candidate for the development of fluoroquinolones determination. (C) 2021 The Society of Powder Technology Japan. Published by Elsevier B.V. and The Society of Powder Technology Japan. All rights reserved.

Automated summary

A high conductivity composite based on TAPB-PDA-COFs/AuNPs was successfully synthesized and used to construct an electrochemical sensor for detecting ENR. The sensor showed good performance with high recoveries and low RSDs, indicating its potential for practical sample detection.