4.6 Article

Synthesis and Functional Characterization of 2-(2,5-Dimethoxyphenyl)-N-(2-fluorobenzyl)ethanamine (25H-NBF) Positional Isomers

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Radiology, Nuclear Medicine & Medical Imaging

Desorption Electrospray Ionization Mass Spectrometry Imaging of Cimbi-36, a 5-HT2A Receptor Agonist, with Direct Comparison to Autoradiography and Positron Emission Tomography

Sophie C. Jacobsen et al.

Summary: The study demonstrates the use of DESI-MSI for imaging of the PET tracer compound Cimbi-36 in brain tissue and compares imaging by DESI-MSI to imaging by autoradiography and PET. The results showed that DESI-MSI had similar distributions of Cimbi-36 to autoradiography in brain tissue, indicating actual binding to certain receptors in the brain. DESI-MSI is suggested as a cost-effective screening tool, which does not rely on labeling of compounds.

MOLECULAR IMAGING AND BIOLOGY (2021)

Article Psychiatry

Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder A Randomized Clinical Trial

Alan K. Davis et al.

Summary: The study showed that psilocybin therapy with psychological support is effective in treating MDD, building on previous findings in patients with cancer and depression, as well as in a nonrandomized study in patients with treatment-resistant depression.

JAMA PSYCHIATRY (2021)

Article Chemistry, Medicinal

Serotonin 2A Receptor (5-HT2AR) Activation by 25H-NBOMe Positional Isomers: In Vitro Functional Evaluation and Molecular Docking

Eline Pottie et al.

Summary: This study investigated the impact of five positional isomers of 25H-NBOMe on 5-HT2AR through experiments and molecular docking techniques. This is the first comparative evaluation of the functional effects of the positioning of methoxy groups in the phenethylamine moiety of NBOMes.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2021)

Review Biochemistry & Molecular Biology

DARK Classics in Chemical Neuroscience: NBOMes

Christian B. M. Poulie et al.

ACS CHEMICAL NEUROSCIENCE (2020)

Article Biochemistry & Molecular Biology

Investigation of the 2,5-Dimethoxy Motif in Phenethylamine Serotonin 2A Receptor Agonists

Emil Marcher-Rorsted et al.

ACS CHEMICAL NEUROSCIENCE (2020)

Article Toxicology

25C-NBF, a new psychoactive substance, has addictive and neurotoxic potential in rodents

Kwang-Hyun Hur et al.

ARCHIVES OF TOXICOLOGY (2020)

Article Pharmacology & Pharmacy

Assessment of biased agonism at the A3 adenosine receptor using β-arrestin and miniGαi recruitment assays

Eline Pottie et al.

BIOCHEMICAL PHARMACOLOGY (2020)

Article Biochemistry & Molecular Biology

Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor

Kuglae Kim et al.

Review Pharmacology & Pharmacy

Effect fingerprinting of new psychoactive substances (NPS): What can we learn from in vitro data?

Laura Hondebrink et al.

PHARMACOLOGY & THERAPEUTICS (2018)

Article Biochemistry & Molecular Biology

NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells

Andrew S. Dixon et al.

ACS CHEMICAL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Synthesis and Structure-Activity Relationships of N-Benzyl Phenethylamines as 5-HT2A/2c Agonists

Martin Hansen et al.

ACS CHEMICAL NEUROSCIENCE (2014)

Article Pharmacology & Pharmacy

Small molecules with antimicrobial activity against E-coli and P-aeruginosa identified by high-throughput screening

R. De La Fuente et al.

BRITISH JOURNAL OF PHARMACOLOGY (2006)

Review Pharmacology & Pharmacy

Hallucinogens

DE Nichols

PHARMACOLOGY & THERAPEUTICS (2004)