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The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity
K. Aigner et al.
ONCOGENE (2007)
Solid pseudopapillary neoplasms of the pancreas show an interruption of the Wnt-signaling pathway and express gene products of 11q
Katharina Tiemann et al.
MODERN PATHOLOGY (2007)
Biology and management of pancreatic cancer
Paula Ghaneh et al.
GUT (2007)
Wnt/β-catenin signaling in development and disease
Hans Clevers
CELL (2006)
被撤回的出版物: Down-regulation of Notch-1 inhibits invasion by inactivation of nuclear Factor-κB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells. (Retracted article. See vol. 78, pg. 5476, 2018)
ZW Wang et al.
CANCER RESEARCH (2006)
Does anyone survive pancreatic ductal adenocarcinoma?: A nationwide study re-evaluating the data of the Finnish Cancer Registry
M Carpelan-Holmström et al.
GUT (2005)
Mammary stem cells, self-renewal pathways, and carcinogenesis
SL Liu et al.
BREAST CANCER RESEARCH (2005)
Mesothelin-specific CD8+ T cell responses provide evidence of in vivo cross-priming by antigen-presenting cells in vaccinated pancreatic cancer patients
AM Thomas et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
The evolution of signalling pathways in animal development
A Pires-daSilva et al.
NATURE REVIEWS GENETICS (2003)
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
Y Iwai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
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