相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy
Meenu Sharma et al.
NATURE COMMUNICATIONS (2020)
Nuclear FOXP3 inhibits tumor growth and induced apoptosis in hepatocellular carcinoma by targeting c-Myc
Zhongqin Gong et al.
ONCOGENESIS (2020)
FOXP3 Inhibitory Peptide P60 Increases Efficacy of Cytokine-induced Killer Cells Against Renal and Pancreatic Cancer Cells
Maria Fitria Setiawan et al.
ANTICANCER RESEARCH (2019)
Treg depletion potentiates checkpoint inhibition in claudin-low breast cancer
Nicholas A. Taylor et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Blockage of FOXP3 transcription factor dimerization and FOXP3/AML1 interaction inhibits T regulatory cell activity: sequence optimization of a peptide inhibitor
Teresa Lozano et al.
ONCOTARGET (2017)
Therapeutic blockade of Foxp3 in experimental breast cancer models
Mariela A. Moreno Ayala et al.
BREAST CANCER RESEARCH AND TREATMENT (2017)
Different molecular complexes that mediate transcriptional induction and repression by FoxP3
Ho-Keun Kwon et al.
NATURE IMMUNOLOGY (2017)
FOXP3 Is a HCC suppressor gene and Acts through regulating the TGF-β/Smad2/3 signaling pathway
Jie-Yi Shi et al.
BMC CANCER (2017)
Targeting inhibition of Foxp3 by a CD28 2′-Fluro oligonucleotide aptamer conjugated to P60-peptide enhances active cancer immunotherapy
Teresa Lozano et al.
BIOMATERIALS (2016)
Epirubicin, Identified Using a Novel Luciferase Reporter Assay for Foxp3 Inhibitors, Inhibits Regulatory T Cell Activity
Hajime Kashima et al.
PLOS ONE (2016)
Peptide therapeutics: current status and future directions
Keld Fosgerau et al.
DRUG DISCOVERY TODAY (2015)
Inhibition of FOXP3/NFAT Interaction Enhances T Cell Function after TCR Stimulation
Teresa Lozano et al.
JOURNAL OF IMMUNOLOGY (2015)
FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis
BeeShin Tan et al.
ONCOTARGET (2014)
Current challenges in peptide-based drug discovery
Laszlo Otvos et al.
FRONTIERS IN CHEMISTRY (2014)
FoxP3 inhibits proliferation and induces apoptosis of gastric cancer cells by activating the apoptotic signaling pathway
Gui-Fen Ma et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Searching for the Achilles heel of FOXP3
Teresa Lozano et al.
FRONTIERS IN ONCOLOGY (2013)
Inhibition of activation induced CD154 on CD4+ CD25- cells: a valid surrogate for human Treg suppressor function
Danika Hill et al.
IMMUNOLOGY AND CELL BIOLOGY (2012)
A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells
Wenxian Fu et al.
NATURE IMMUNOLOGY (2012)
Transcription factor Foxp3 and its protein partners form a complex regulatory network
Dipayan Rudra et al.
NATURE IMMUNOLOGY (2012)
Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function
Xiaomin Song et al.
CELL REPORTS (2012)
Sub-optimal CD4+ T-cell activation triggers autonomous TGF-β-dependent conversion to Foxp3+ regulatory T cells
Vanessa G. Oliveira et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Stability of peptides and therapeutic success in cancer
Marlene Pernot et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2011)
Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells
Hozefa S. Bandukwala et al.
IMMUNITY (2011)
Tumor suppressor and T-regulatory functions of Foxp3 are mediated through separate signaling pathways
Emil Heinze et al.
ONCOLOGY LETTERS (2011)
Up-regulation of Foxp3 inhibits cell proliferation, migration and invasion in epithelial ovarian cancer
Hai-Yan Zhang et al.
CANCER LETTERS (2010)
Signalling through FOXP3 as an X-linked tumor suppressor
Hiroto Katoh et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
A Peptide Inhibitor of FOXP3 Impairs Regulatory T Cell Activity and Improves Vaccine Efficacy in Mice
Noelia Casares et al.
JOURNAL OF IMMUNOLOGY (2010)
Identification of new FOXP3 mutations and prenatal diagnosis of IPEX syndrome
Radu Harbuz et al.
PRENATAL DIAGNOSIS (2010)
Somatic Single Hits Inactivate the X-Linked Tumor Suppressor FOXP3 in the Prostate
Lizhong Wang et al.
CANCER CELL (2009)
Clinical Heterogeneity in Patients With FOXP3 Mutations Presenting With Permanent Neonatal Diabetes
Oscar Rubio-Cabezas et al.
DIABETES CARE (2009)
FOXP3 Inhibits Activation-Induced NFAT2 Expression in T Cells Thereby Limiting Effector Cytokine Expression
Troy R. Torgerson et al.
JOURNAL OF IMMUNOLOGY (2009)
Domain Requirements and Sequence Specificity of DNA Binding for the Forkhead Transcription Factor FOXP3
Kian Peng Koh et al.
PLOS ONE (2009)
FoxP3 maintains Treg unresponsiveness by selectively inhibiting the promoter DNA-binding activity of AP-1
Sang-Myeong Lee et al.
BLOOD (2008)
FOXP3 is an X-linked breast cancer suppressor gene and an important repressor of the HER-2/ErbB2 oncogene
Tao Zuo et al.
CELL (2007)
Severe food allergy as a variant of IPEX syndrome caused by a deletion in a noncoding region of the FOXP3 gene
Troy R. Torgerson et al.
GASTROENTEROLOGY (2007)
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
Masahiro Ono et al.
NATURE (2007)
FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression
Bin Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
Luke M. Williams et al.
NATURE IMMUNOLOGY (2007)
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
Yisong Y. Wan et al.
NATURE (2007)
Transient expression of FOXP3 in human activated nonregulatory CD4(+) T cells
Jun Wang et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
FOXP3 is a novel transcriptional repressor for the breast cancer oncogene SKP2
Tao Zuo et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Analysis of FOXP3 reveals multiple domains required for its function as a transcriptional repressor
Jared E. Lopes et al.
JOURNAL OF IMMUNOLOGY (2006)
FOXP3 controls regulatory T cell function through cooperation with NFAT
Yongqing Wu et al.
CELL (2006)
The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells
Wook-Jin Chae et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Defective regulatory and effector T cell functions in patients with FOXP3 mutations
Rosa Bacchetta et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Regulatory T cells, tumour immunity and immunotherapy
WP Zou
NATURE REVIEWS IMMUNOLOGY (2006)
Foxp3 interacts with nuclear factor of activated T cells and NF-κB to repress cytokine gene expression and effector functions of T helper cells
E Bettelli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
TJ Curiel et al.
NATURE MEDICINE (2004)
Foxp3 expressing CD4+CD25high regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
M Viguier et al.
JOURNAL OF IMMUNOLOGY (2004)
CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-γ-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination
N Casares et al.
JOURNAL OF IMMUNOLOGY (2003)
Mutational analysis of the FOXP3 gene and evidence for genetic heterogeneity in the immunodysregulation, polyendocrinopathy, enteropathy syndrome
CJ Owen et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
UK Liyanage et al.
JOURNAL OF IMMUNOLOGY (2002)
Quantitation of the tumor-targeting properties of antibody fragments conjugated to cell-permeating HIV-1 TAT peptides
U Niesner et al.
BIOCONJUGATE CHEMISTRY (2002)
Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation
LA Schubert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25+ regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
RPM Sutmuller et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
A rare polyadenylation signal mutation of the FOXP3 gene (AAUAAA→AAUGAA) leads to the IPEX syndrome
CL Bennett et al.
IMMUNOGENETICS (2001)
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
RS Wildin et al.
NATURE GENETICS (2001)
分享论文
