期刊
BIOACTIVE MATERIALS
卷 6, 期 2, 页码 568-578出版社
KEAI PUBLISHING LTD
DOI: 10.1016/j.bioactmat.2020.08.013
关键词
Magnesium; Ti3C2 Mxene; Coating; Photoresponsive; Degradation
资金
- Natural Science Fund of Hubei Province [2018CFA064]
- National Science Fund for Distinguished Young Scholars [51925104]
- National Natural Science Foundation of China [51671081, 51871162]
- Hong Kong ITC [ITS/287/17, GHX/002/14SZ]
- Health and Medical Research Fund [03142446]
A PLGA/Ti3C2 hybrid coating was successfully deposited on magnesium-strontium (Mg-Sr) alloys, significantly reducing corrosion current density and increasing it after laser irradiation. Local hyperthermia induced PLGA volume expansion, enhancing electrolyte penetration and improving the biocompatibility of the Mg-Sr alloy.
A PLGA/Ti3C2 hybrid coating was successfully deposited on the surface of magnesium-strontium (Mg-Sr) alloys. Compared with the corrosion current density (i(corr)) of the Mg-Sr alloy (7.13 x 10(-5) A/cm(2)), the modified samples (Mg/PLGA/Ti3C2) was lower by approximately four orders of magnitude (7.65 x 10(-9) A/cm(2)). After near infrared 808 nm laser irradiation, the i(corr) of the modified samples increased to 3.48 x 10(-7) A/cm(2). The mechanism is that the local hyperthermia induced the free volume expansion of PLGA, and the increase in intermolecular gap enhanced the penetration of electrolytes. Meanwhile, the cytotoxicity study showed that the hybrid coating endowed the Mg-Sr alloy with enhanced biocompatibility.
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