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Barbara Mroczko et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
MicroRNA Profiling of CSF Reveals Potential Biomarkers to Detect Alzheimer's Disease
Johannes Denk et al.
PLOS ONE (2015)
Progranulin and Amyloid-beta Levels: Relationship to Neuropsychology in Frontotemporal and Alzheimer's Disease
Peter Koertvelyessy et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
GAP-43 in synaptic plasticity: molecular perspectives
Matthew R. Holahan
RESEARCH AND REPORTS IN BIOCHEMISTRY (2015)
Diagnostic Accuracy of Cerebrospinal Fluid Amyloid-β Isoforms for Early and Differential Dementia Diagnosis
Hanne Struyfs et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
Cerebrospinal Fluid Biomarkers Distinguish Postmortem-Confirmed Alzheimer's Disease from Other Dementias and Healthy Controls in the OPTIMA Cohort
Jeffrey L. Seeburger et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
The Role of Visinin-Like Protein-1 in the Pathophysiology of Alzheimer's Disease
Magdalena Groblewska et al.
JOURNAL OF ALZHEIMERS DISEASE (2015)
Staging TDP-43 pathology in Alzheimer's disease
Keith A. Josephs et al.
ACTA NEUROPATHOLOGICA (2014)
R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia
Catherine F. Slattery et al.
ALZHEIMERS & DEMENTIA (2014)
Cerebrospinal fluid BACE1 activity and markers of amyloid precursor protein metabolism and axonal degeneration in Alzheimer's disease
Robert Perneczky et al.
ALZHEIMERS & DEMENTIA (2014)
Increased CSF α-synuclein levels in Alzheimer's disease: Correlation with tau levels
Sylvie Slaets et al.
ALZHEIMERS & DEMENTIA (2014)
Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: A long-range point of view beyond 2020
Harald Hampel et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Phosphorylated Tau-Aβ42 Ratio as a Continuous Trait for Biomarker Discovery for Early-Stage Alzheimer's Disease in Multiplex Immunoassay Panels of Cerebrospinal Fluid
Oscar Harari et al.
BIOLOGICAL PSYCHIATRY (2014)
MicroRNA-384 regulates both amyloid precursor protein and β-secretase expression and is a potential biomarker for Alzheimer's disease
Chen-Geng Liu et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2014)
MicroRNAs in Plasma and Cerebrospinal Fluid as Potential Markers for Alzheimer's Disease
Takehiro Kiko et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Cerebrospinal Fluid Level of YKL-40 Protein in Preclinical and Prodromal Alzheimer's Disease
Anna Antonell et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Circulating miRNAs as Potential Biomarkers in Alzheimer's Disease
Daniela Galimberti et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Lack of Genetic Association Between TREM2 and Late-Onset Alzheimer's Disease in a Japanese Population
Akinori Miyashita et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria
Bruno Dubois et al.
LANCET NEUROLOGY (2014)
SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease
Ann Brinkmalm et al.
MOLECULAR NEURODEGENERATION (2014)
Oligomeric Aβ-induced synaptic dysfunction in Alzheimer's disease
Shichun Tu et al.
MOLECULAR NEURODEGENERATION (2014)
CSF biomarkers for Alzheimer's pathology and the effect size of APOE ε4
U. Andreasson et al.
MOLECULAR PSYCHIATRY (2014)
MRI for Iron Mapping in Alzheimer's Disease
Christian Langkammer et al.
NEURODEGENERATIVE DISEASES (2014)
A comparison of early diagnostic utility of Alzheimer disease biomarkers in brain magnetic resonance and cerebrospinal fluid
J. A. Monge Argiles et al.
NEUROLOGIA (2014)
Higher risk of progression to dementia in mild cognitive impairment cases who revert to normal
Rosebud O. Roberts et al.
NEUROLOGY (2014)
CSF neurofilament light differs in neurodegenerative diseases and predicts severity and survival
Tobias Skillback et al.
NEUROLOGY (2014)
Oxidative Stress and Metabolic Syndrome: Cause or Consequence of Alzheimer's Disease?
Diana Luque-Contreras et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
Profiles of Extracellular miRNA in Cerebrospinal Fluid and Serum from Patients with Alzheimer's and Parkinson's Diseases Correlate with Disease Status and Features of Pathology
Kasandra Burgos et al.
PLOS ONE (2014)
Alpha-synuclein biology in Lewy body diseases
Woojin Scott Kim et al.
ALZHEIMERS RESEARCH & THERAPY (2014)
Detection of Misfolded Aβ Oligomers for Sensitive Biochemical Diagnosis of Alzheimer's Disease
Natalia Salvadores et al.
CELL REPORTS (2014)
Biomarkers in neurodegenerative disorders: translating research into clinical practice
Manuel Menendez-Gonzalez
FRONTIERS IN AGING NEUROSCIENCE (2014)
Meta-review of CSF core biomarkers in Alzheimer's disease: the state-of-the-art after the new revised diagnostic criteria
Daniel Ferreira et al.
FRONTIERS IN AGING NEUROSCIENCE (2014)
Protein phosphatase 2A dysfunction in Alzheimer's disease
Jean-Marie Sontag et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2014)
Early experience, structural dissociation, and emotional dysregulation in borderline personality disorder: the role of insecure and disorganized attachment
Dolores Mosquera et al.
BORDERLINE PERSONALITY DISORDER AND EMOTION DYSREGULATION (2014)
Increased Levels of Chitotriosidase and YKL-40 in Cerebrospinal Fluid from Patients with Alzheimer's Disease
Christoffer Rosen et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA (2014)
CSF α-synuclein improves diagnostic and prognostic performance of CSF tau and Aβ in Alzheimer's disease
Jon B. Toledo et al.
ACTA NEUROPATHOLOGICA (2013)
Plasma Proteomics for the Identification of Alzheimer Disease
Liang-Hao Guo et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2013)
Role of chemokine CCL2 and its receptor CCR2 in neurodegenerative diseases
Shambhunath Bose et al.
ARCHIVES OF PHARMACAL RESEARCH (2013)
Dyslipidemia and the Risk of Alzheimer's Disease
Christiane Reitz
CURRENT ATHEROSCLEROSIS REPORTS (2013)
Evaluation of the Cerebrospinal Fluid Amyloid-β1-42/Amyloid-β1-40 Ratio Measured by Alpha-LISA to Distinguish Alzheimer's Disease from Other Dementia Disorders
Magdalena Nutu et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2013)
Heart-type fatty acid binding protein as an early marker for myocardial infarction: systematic review and meta-analysis
Christopher Carroll et al.
EMERGENCY MEDICINE JOURNAL (2013)
Heart-type fatty acid binding protein and vascular endothelial growth factor: cerebrospinal fluid biomarker candidates for Alzheimer's disease
Liang-Hao Guo et al.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2013)
Cerebrospinal Fluid Aβ1-40 Improves Differential Dementia Diagnosis in Patients with Intermediate P-tau181P Levels
Sylvie Slaets et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
alpha-Synuclein in Cerebrospinal Fluid of Alzheimer's Disease and Mild Cognitive Impairment
Ane Korff et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
CSF levels of the neuronal injury biomarker visinin-like protein-1 in Alzheimer's disease and dementia with Lewy bodies
Xinni Luo et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Alzheimer's A42 and A40 peptides form interlaced amyloid fibrils
Lei Gu et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Elevated Osteopontin Levels in Mild Cognitive Impairment and Alzheimer's Disease
Yuan Sun et al.
MEDIATORS OF INFLAMMATION (2013)
Reduced expression of hsa-miR-27a-3p in CSF of patients with Alzheimer disease
Carlo Sala Frigerio et al.
NEUROLOGY (2013)
GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer's Disease
Carlos Cruchaga et al.
NEURON (2013)
Variant TREM2 as Risk Factor for Alzheimer's Disease
Harald Neumann et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
Thorlakur Jonsson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
TREM2 Variants in Alzheimer's Disease
Rita Guerreiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
The Correlation of Hippocampal T2-Mapping with Neuropsychology Test in Patients with Alzheimer's Disease
Zhuren Luo et al.
PLOS ONE (2013)
The Diagnostic Value of CSF α-Synuclein in the Differential Diagnosis of Dementia with Lewy Bodies vs. Normal Subjects and Patients with Alzheimer's Disease
Elisabeth Kapaki et al.
PLOS ONE (2013)
Recent developments of protein kinase inhibitors as potential AD therapeutics
Volkmar Tell et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
Alpha-synuclein in the Cerebrospinal Fluid Differentiates Synucleinopathies (Parkinson Disease, Dementia With Lewy Bodies, Multiple System Atrophy) From Alzheimer Disease
Fuyuki Tateno et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2012)
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
Bradley T. Hyman et al.
ALZHEIMERS & DEMENTIA (2012)
Cerebrospinal Fluid Levels of β-Amyloid 1-42, but Not of Tau, Are Fully Changed Already 5 to 10 Years Before the Onset of Alzheimer Dementia
Peder Buchhave et al.
ARCHIVES OF GENERAL PSYCHIATRY (2012)
Biochemical Increase in Phosphorylated Alpha-Synuclein Precedes Histopathology of Lewy-Type Synucleinopathies
Lih-Fen Lue et al.
BRAIN PATHOLOGY (2012)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Progranulin: A Proteolytically Processed Protein at the Crossroads of Inflammation and Neurodegeneration
Basar Cenik et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Neurofilaments at a glance
Aidong Yuan et al.
JOURNAL OF CELL SCIENCE (2012)
Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
Peter T. Nelson et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2012)
The SNARE complex in neuronal and sensory cells
Neeliyath A. Ramakrishnan et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2012)
Serial CSF sampling in Alzheimer's disease: specific versus non-specific markers
Maartje I. Kester et al.
NEUROBIOLOGY OF AGING (2012)
CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings
T. T. Seppala et al.
NEUROLOGY (2012)
CSF VILIP-1 predicts rates of cognitive decline in early Alzheimer disease
R. Tarawneh et al.
NEUROLOGY (2012)
CCL2 Is Associated with a Faster Rate of Cognitive Decline during Early Stages of Alzheimer's Disease
Karin Westin et al.
PLOS ONE (2012)
Metabolite Profiling of Alzheimer's Disease Cerebrospinal Fluid
Christian Czech et al.
PLOS ONE (2012)
Neurogranin Targets Calmodulin and Lowers the Threshold for the Induction of Long-Term Potentiation
Ling Zhong et al.
PLOS ONE (2012)
Synapses and Alzheimer's Disease
Morgan Sheng et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Fluid Biomarkers in Alzheimer Disease
Kaj Blennow et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
Osteopontin: A key link between immunity, inflammation and the central nervous system
Amanda Brown
TRANSLATIONAL NEUROSCIENCE (2012)
The visinin-like proteins VILIP-1 and VILIP-3 in Alzheimer's disease-old wine in new bottles
Karl H. Braunewell
FRONTIERS IN MOLECULAR NEUROSCIENCE (2012)
The anatomical and cellular basis of immune surveillance in the central nervous system
Richard M. Ransohoff et al.
NATURE REVIEWS IMMUNOLOGY (2012)
The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
Marilyn S. Albert et al.
ALZHEIMERS & DEMENTIA (2011)
The Alzheimer’s Disease Neuroimaging Initiative: A review of papers published since its inception
Michael W. Weiner et al.
Alzheimers & Dementia (2011)
Visinin-like Protein-1: Diagnostic and Prognostic Biomarker in Alzheimer Disease
Rawan Tarawneh et al.
ANNALS OF NEUROLOGY (2011)
Comparison of Analytical Platforms for Cerebrospinal Fluid Measures of β-Amyloid 1-42, Total tau, and P-tau181 for Identifying Alzheimer Disease Amyloid Plaque Pathology
Anne M. Fagan et al.
ARCHIVES OF NEUROLOGY (2011)
Chemokines in CSF of Alzheimer's disease patients
Joice Dias Correa et al.
ARQUIVOS DE NEURO-PSIQUIATRIA (2011)
Reduced plasma levels of P-selectin and L-selectin in a pilot study from Alzheimer disease: relationship with neuro-degeneration
Massimiliano M. Corsi et al.
BIOGERONTOLOGY (2011)
Tau and p-tau as CSF biomarkers in dementia: a meta-analysis
Argonde C. van Harten et al.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2011)
Carbohydrate-binding motif in chitinase 3-like 1 (CHI3L1/YKL-40) specifically activates Akt signaling pathway in colonic epithelial cells
Chun-Chuan Chen et al.
CLINICAL IMMUNOLOGY (2011)
Progression from Mild to Pronounced MCI Is Not Associated with Cerebrospinal Fluid Biomarker Deviations
A. Wallin et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2011)
Distinguishing Alzheimer's disease from other major forms of dementia
Stella Karantzoulis et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2011)
Decreased sA beta PP beta, A beta(38), and A beta(40) Cerebrospinal Fluid Levels in Frontotemporal Dementia
Audrey Gabelle et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Increased CSF-BACE1 Activity Associated with Decreased Hippocampus Volume in Alzheimer's Disease
Michael Ewers et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Review and Meta-Analysis of Biomarkers and Diagnostic Imaging in Alzheimer's Disease
Lisa M. Bloudek et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
The Role of Osteopontin in Neurodegenerative Diseases
Miryam Carecchio et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Progranulin and TDP-43: Mechanistic Links and Future Directions
Samir Kumar-Singh
JOURNAL OF MOLECULAR NEUROSCIENCE (2011)
Cellular Effects of Progranulin in Health and Disease
Louis De Muynck et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2011)
Accumulation of Transactive Response DNA Binding Protein 43 in Mild Cognitive Impairment and Alzheimer Disease
Cyntia Tremblay et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2011)
Multiplexed Immunoassay Panel Identifies Novel CSF Biomarkers for Alzheimer's Disease Diagnosis and Prognosis
Rebecca Craig-Schapiro et al.
PLOS ONE (2011)
GFAP in health and disease
J. Middeldorp et al.
PROGRESS IN NEUROBIOLOGY (2011)
Identifying and validating biomarkers for Alzheimer's disease
Christian Humpel
TRENDS IN BIOTECHNOLOGY (2011)
Synaptic Vesicle Exocytosis
Thomas C. Suedhof et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)
Astrocytes: biology and pathology
Michael V. Sofroniew et al.
ACTA NEUROPATHOLOGICA (2010)
Cerebral atrophy, apolipoprotein E ε4, and rate of decline in everyday function among patients with amnestic mild cognitive impairment
Ozioma C. Okonkwo et al.
ALZHEIMERS & DEMENTIA (2010)
YKL-40: A Novel Prognostic Fluid Biomarker for Preclinical Alzheimer's Disease
Rebecca Craig-Schapiro et al.
BIOLOGICAL PSYCHIATRY (2010)
Neurogranin in cerebrospinal fluid as a marker of synaptic degeneration in Alzheimer's disease
Annika Thorsell et al.
BRAIN RESEARCH (2010)
The Cerebrospinal Fluid Amyloid β42/40 Ratio in the Differentiation of Alzheimer's Disease from Non-Alzheimer's Dementia
P. E. Spies et al.
CURRENT ALZHEIMER RESEARCH (2010)
Alzheimer Disease
Rudy J. Castellani et al.
DM DISEASE-A-MONTH (2010)
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio
Irina Kuperstein et al.
EMBO JOURNAL (2010)
Total and phosphorylated tau protein as biological markers of Alzheimer's disease
Harald Hampel et al.
EXPERIMENTAL GERONTOLOGY (2010)
Fatty acid binding proteins in brain development and disease
Rong-Zong Liu et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2010)
Osteopontin is Increased in the Cerebrospinal Fluid of Patients with Alzheimer's Disease and Its Levels Correlate with Cognitive Decline
Cristoforo Comi et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
CSF alpha-Synuclein Does Not Discriminate Dementia with Lewy Bodies from Alzheimer's Disease
Fransje E. Reesink et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks
Bridgette D. Semple et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2010)
A highly sensitive electrochemiluminescence immunoassay for the neurofilament heavy chain protein
Jens Kuhle et al.
JOURNAL OF NEUROIMMUNOLOGY (2010)
Differential levels of α-synuclein, β-amyloid42 and tau in CSF between patients with dementia with Lewy bodies and Alzheimer's disease
Kensaku Kasuga et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2010)
Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
Clifford R. Jack et al.
LANCET NEUROLOGY (2010)
Neuropathology of Alzheimer's Disease
Daniel P. Perl
MOUNT SINAI JOURNAL OF MEDICINE (2010)
TAR DNA-binding protein 43 in neurodegenerative disease
Alice S. Chen-Plotkin et al.
NATURE REVIEWS NEUROLOGY (2010)
Cerebrospinal Fluid Concentrations of Functionally Important Amino Acids and Metabolic Compounds in Patients with Mild Cognitive Impairment and Alzheimer's Disease
Elmar Kaiser et al.
NEURODEGENERATIVE DISEASES (2010)
Meta-analysis of CSF and MRI biomarkers for detecting preclinical Alzheimer's disease
B. Schmand et al.
PSYCHOLOGICAL MEDICINE (2010)
Preferentially Increased Nitration of α-Synuclein at Tyrosine-39 in a Cellular Oxidative Model of Parkinson's Disease
Steven R. Danielson et al.
ANALYTICAL CHEMISTRY (2009)
A Novel Recessive NEFL Mutation Causes a Severe, Early-Onset Axonal Neuropathy
Sabrina W. Yum et al.
ANNALS OF NEUROLOGY (2009)
Cerebrospinal Fluid Biomarker Signature in Alzheimer's Disease Neuroimaging Initiative Subjects
Leslie M. Shaw et al.
ANNALS OF NEUROLOGY (2009)
Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases
Catherine M. Cahill et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)
CSF α-synuclein levels in dementia with Lewy bodies and Alzheimer's disease
Moeko Noguchi-Shinohara et al.
BRAIN RESEARCH (2009)
Osteopontin: A multifunctional protein at the crossroads of inflammation, atherosclerosis, and vascular calcification
Hyun-Ju Cho et al.
CURRENT ATHEROSCLEROSIS REPORTS (2009)
Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options
Bayani Uttara et al.
CURRENT NEUROPHARMACOLOGY (2009)
CSF biomarker profile and diagnostic value in vascular dementia
G. P. Paraskevas et al.
EUROPEAN JOURNAL OF NEUROLOGY (2009)
Glial Fibrillary Acidic Protein and Protein S-100B: Different Concentration Pattern of Glial Proteins in Cerebrospinal Fluid of Patients with Alzheimer's Disease and Creutzfeldt-Jakob Disease
Sarah Jesse et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Correlation of Iron in the Hippocampus with MMSE in Patients with Alzheimer's Disease
Bei Ding et al.
JOURNAL OF MAGNETIC RESONANCE IMAGING (2009)
CSF phosphorylated tau in the diagnosis and prognosis of mild cognitive impairment and Alzheimer's disease: a meta-analysis of 51 studies
A. J. Mitchell
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2009)
Neurofilaments Form a Highly Stable Stationary Cytoskeleton after Reaching a Critical Level in Axons
Aidong Yuan et al.
JOURNAL OF NEUROSCIENCE (2009)
Calcium signaling in neurodegeneration
Philippe Marambaud et al.
MOLECULAR NEURODEGENERATION (2009)
Cerebrospinal fluid α-synuclein in neurodegenerative disorders-A marker of synapse loss?
Annika Ohrfelt et al.
NEUROSCIENCE LETTERS (2009)
Quantitative MR Phase-corrected Imaging to Investigate Increased Brain Iron Deposition of Patients with Alzheimer Disease
Wen-zhen Zhu et al.
RADIOLOGY (2009)
Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) as a biological candidate marker of Alzheimer's disease
Harald Hampel et al.
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION (2009)
Regulation of innate immune responses in the brain
Serge Rivest
NATURE REVIEWS IMMUNOLOGY (2009)
Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease
Henrik Zetterberg et al.
ARCHIVES OF NEUROLOGY (2008)
Increased CSF-BACE 1 activity is associated with ApoE-ε4 genotype in subjects with mild cognitive impairment and Alzheimer's disease
Michael Ewers et al.
BRAIN (2008)
Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation
Laura Piccio et al.
BRAIN (2008)
Decrease in age-adjusted cerebrospinal fluid β-secretase activity in Alzheimer's subjects
Guoxin Wu et al.
CLINICAL BIOCHEMISTRY (2008)
The brain injury biomarker VLP-1 is increased in the cerebrospinal fluid of Alzheimer disease patients
Jin-Moo Lee et al.
CLINICAL CHEMISTRY (2008)
Osteopontin: Role in immune regulation and stress responses
Kathryn X. Wang et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2008)
Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration
Brit Mollenhauer et al.
EXPERIMENTAL NEUROLOGY (2008)
TDP-43 in neurodegenerative disorders
Casey Cook et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2008)
Novel cerebrospinal fluid biomarkers of axonal degeneration in frontotemporal dementia
Niklas Mattsson et al.
MOLECULAR MEDICINE REPORTS (2008)
Genetic variability in progranulin contributes to risk for clinically diagnosed Alzheimer disease
N. Brouwers et al.
NEUROLOGY (2008)
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
Jemeen Sreedharan et al.
SCIENCE (2008)
Do CSF total tau, phosphorylated tau, and beta-amyloid 42 help to predict progression of mild cognitive impairment to Alzheimer's disease? A systematic review and meta-analysis of the literature
Breno S. O. Diniz et al.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY (2008)
Ubiquitination of α-synuclein by Siah-1 promotes α-synuclein aggregation and apoptotic cell death
James T. Lee et al.
HUMAN MOLECULAR GENETICS (2008)
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions
Nigel J. Cairns et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
TDP43 is a human low molecular weight neurofilament (hNFL) mRNA-binding protein
Michael J. Strong et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2007)
Amyloid β peptide ratio 42/40 but not Aβ42 correlates with phospho-Tau in patients with low- and high-CSF Aβ40 load
Jens Wiltfang et al.
JOURNAL OF NEUROCHEMISTRY (2007)
TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease
Catalina Amador-Ortiz et al.
ANNALS OF NEUROLOGY (2007)
Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment
Anja H. Simonsen et al.
ARCHIVES OF NEUROLOGY (2007)
Cerebrospinal fluid tau/β-amyloid42 ratio as a prediction of cognitive decline in nondemented older adults
Anne M. Fagan et al.
ARCHIVES OF NEUROLOGY (2007)
Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain
John K. Wung et al.
CURRENT ALZHEIMER RESEARCH (2007)
High plasma osteopontin levels in patients with inflammatory bowel disease
Ryosuke Mishima et al.
JOURNAL OF CLINICAL GASTROENTEROLOGY (2007)
Aβ40 inhibits amyloid deposition in vivo
Jungsu Kim et al.
JOURNAL OF NEUROSCIENCE (2007)
A systematic review and meta-analysis of CSF neurofilament protein levels as biomarkers in dementia
A. Petzold et al.
NEURODEGENERATIVE DISEASES (2007)
Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: Marker candidates for dementia with Lewy bodies
Brit Mollenhauer et al.
NEURODEGENERATIVE DISEASES (2007)
Structural principles of tau and the paired helical filaments of Alzheimer's disease
Eckhard Mandelkow et al.
BRAIN PATHOLOGY (2007)
CSF neurofilaments in frontotemporal dementia compared with early onset Alzheimer's disease and controls
Yolande A. L. Pijnenburg et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2007)
Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling
Robert D. Burgoyne
NATURE REVIEWS NEUROSCIENCE (2007)
Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment
Zhenyu Zhong et al.
ARCHIVES OF GENERAL PSYCHIATRY (2007)
Selective loss of synaptic proteins in Alzheimer's disease:: Evidence for an increased severity with APOE ε4
Rudi K. Tannenberg et al.
NEUROCHEMISTRY INTERNATIONAL (2006)
Tau-dependent microtubule disassembly initiated by prefibrillar β-amyloid
Michelle E. King et al.
JOURNAL OF CELL BIOLOGY (2006)
CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease
Katharina Buerger et al.
BRAIN (2006)
The roles of intracellular protein-degradation pathways in neurodegeneration
David C. Rubinsztein
NATURE (2006)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment
Stephen W. Scheff et al.
NEUROBIOLOGY OF AGING (2006)
Molecular mechanisms, biological actions, and neuropharmacology of the growth-associated protein GAP-43
John B. Denny
CURRENT NEUROPHARMACOLOGY (2006)
Mild cognitive impairment: An opportunity to identify patients at high risk for progression to Alzheimer's disease
Allan Levey et al.
CLINICAL THERAPEUTICS (2006)
Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment
Scott E. Counts et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)
Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway
J Kzhyshkowska et al.
BLOOD (2006)
Intrathecal chemokine synthesis in mild cognitive impairment and Alzheimer disease
D Galimberti et al.
ARCHIVES OF NEUROLOGY (2006)
Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study
O Hansson et al.
LANCET NEUROLOGY (2006)
The neurofilament heavy chain (NfH(SMI35)) in the cerebrospinal fluid diagnosis of Alzheimer's disease
Johannes Brettschneider et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2006)
alpha-Synuclein structure, posttranslational modification and alternative splicing as aggregation enhancers
Katrin Beyer
ACTA NEUROPATHOLOGICA (2006)
Synaptic activity regulates interstitial fluid amyloid-β levels in vivo
JR Cirrito et al.
NEURON (2005)
Alternative splicing of SNAP-25 regulates secretion through nonconservative substitutions in the SNARE domain
G Nagy et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
F Liu et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Aβ42 is essential for parenchymal and vascular amyloid deposition in mice
E McGowan et al.
NEURON (2005)
Elevation of plasma osteopontin concentration is correlated with disease activity in patients with systemic lupus erythematosus
CK Wong et al.
RHEUMATOLOGY (2005)
CSF Aβ42 and tau or phosphorylated tau and prediction of progressive mild cognitive impairment
SK Herukka et al.
NEUROLOGY (2005)
Role of tau protein in both physiological and pathological conditions
J Avila et al.
PHYSIOLOGICAL REVIEWS (2004)
Neurochemical diagnosis of Alzheimer's dementia by CSF Aβ42, Aβ42/Aβ40 ratio and total tau
P Lewczuk et al.
NEUROBIOLOGY OF AGING (2004)
High serum YKL-40 level in patients with small cell lung cancer is related to early death
JS Johansen et al.
LUNG CANCER (2004)
Iron, brain ageing and neurodegenerative disorders
L Zecca et al.
NATURE REVIEWS NEUROSCIENCE (2004)
Subfield-specific increase in brain growth protein in postmortem hippocampus of Alzheimer's patients
JL Rekart et al.
NEUROSCIENCE (2004)
Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases
DJ Selkoe
NATURE CELL BIOLOGY (2004)
Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia
G Sessa et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
The chemokine CXCL10 modulates excitatory activity and intracellular calcium signaling in cultured hippocampal neurons
TE Nelson et al.
JOURNAL OF NEUROIMMUNOLOGY (2004)
Measurement of α- and β-secretase cleaved amyloid precursor protein in cerebrospinal fluid from Alzheimer patients
A Olsson et al.
EXPERIMENTAL NEUROLOGY (2003)
High serum YKL-40 levels in patients with primary breast cancer is related to short recurrence free survival
JS Johansen et al.
BREAST CANCER RESEARCH AND TREATMENT (2003)
Biological markers for therapeutic trials in Alzheimer's disease - Proceedings of the biological markers working group; NIA initiative on neuroimaging in Alzheimer's disease
RA Frank et al.
NEUROBIOLOGY OF AGING (2003)
Decreased β-amyloid1-42 and increased tau levels in cerebrospinal fluid of patients with Alzheimer disease
T Sunderland et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)
Cerebrospinal fluid levels of total-tau, phospho-tau and Aβ42 predicts development of Alzheimer's disease in patients with mild cognitive impairment
N Andreasen et al.
ACTA NEUROLOGICA SCANDINAVICA (2003)
Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
LB Yang et al.
NATURE MEDICINE (2003)
Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype
J Paloneva et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2002)
β-secretase protein and activity are increased in the neocortex in Alzheimer disease
H Fukumoto et al.
ARCHIVES OF NEUROLOGY (2002)
The CXCR3 binding chemokine IP-10/CXCL10: Structure and receptor interactions
V Booth et al.
BIOCHEMISTRY (2002)
SNAREs and Munc18 in synaptic vesicle fusion
J Rizo et al.
NATURE REVIEWS NEUROSCIENCE (2002)
New insights into the structure and function of fatty acid-binding proteins
AW Zimmerman et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2002)
Relationships among cerebrospinal fluid biomarkers in dementia of the Alzheimer type
JG Csernansky et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2002)
Increased expression of the amyloid precursor β-secretase in Alzheimer's disease
RMD Holsinger et al.
ANNALS OF NEUROLOGY (2002)
Lipid droplet binding and oligomerization properties of the Parkinson's disease protein α-synuclein
NB Cole et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Cerebrospinal fluid phospho-tau, total tau and beta-amyloid(1-42) in the differentiation between Alzheimer's disease and vascular dementia
K Nagga et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2002)
Synaptic pathology in prefrontal cortex is present only with severe dementia in Alzheimer disease
SL Minger et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2001)
Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9
E Buratti et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The cerebrospinal fluid levels of tau, growth-associated protein-43 and soluble amyloid precursor protein correlate in Alzheimer's disease, reflecting a common pathophysiological process
M Sjögren et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2001)
Synaptosomal proteins, beta-soluble N-ethylmaleimide-sensitive factor attachment protein (beta-SNAP), gamma-SNAP and synaptotagmin 1 in brain of patients with Down syndrome and Alzheimer's disease
BC Yoo et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2001)
Quantitative assessment of possible age-related change in synaptic numbers in the human frontal cortex
SW Scheff et al.
NEUROBIOLOGY OF AGING (2001)
Activated Fyn phosphorylates α-synuclein at tyrosine residue 125
T Nakamura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
Altered expression of synaptic proteins occurs early during progression of Alzheimer's disease
E Masliah et al.
NEUROLOGY (2001)
The cerebrospinal fluid level of glial fibrillary acidic protein is increased in cerebrospinal fluid from Alzheimer's disease patients and correlates with severity of dementia
R Fukuyama et al.
EUROPEAN NEUROLOGY (2001)
Osteopontin: a key cytokine in cell-mediated and granulomatous inflammation
A O'Regan et al.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2000)
Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000)
LF Eng et al.
NEUROCHEMICAL RESEARCH (2000)
The C2B domain of synaptotagmin is a Ca2+-sensing module essential for exocytosis
RC Desai et al.
JOURNAL OF CELL BIOLOGY (2000)
Expression of the chemokine receptor CXCR3 on neurons and the elevated expression of its ligand IP-10 in reactive astrocytes: in vitro ERK1/2 activation and role in Alzheimer's disease
MQ Xia et al.
JOURNAL OF NEUROIMMUNOLOGY (2000)
Selective regional loss of exocytotic presynaptic vesicle proteins in Alzheimer's disease brains
CI Sze et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2000)
Synucleins are developmentally expressed, and α-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons
DD Murphy et al.
JOURNAL OF NEUROSCIENCE (2000)
Growth-associated protein GAP-43 in the frontal cortex and in the hippocampus in Alzheimer's disease: an immunohistochemical and quantitative study
N Bogdanovic et al.
JOURNAL OF NEURAL TRANSMISSION (2000)
Age-dependent change in the levels of A beta 40 and A beta 42 in cerebrospinal fluid from control subjects, and a decrease in the ratio of A beta 42 to A beta 40 level in cerebrospinal fluid from Alzheimer's disease patients
R Fukuyama et al.
EUROPEAN NEUROLOGY (2000)
Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease
PD Mehta et al.
ARCHIVES OF NEUROLOGY (2000)