4.6 Editorial Material

The need for a cardionephrology subspecialty

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Summary: Heart failure is a major cause of morbidity and mortality in chronic kidney disease patients. Myocardial interstitial fibrosis (MIF), resulting from altered collagen turnover, contributes to the development of heart failure. Various mechanisms in different stages of chronic kidney disease may affect fibroblasts and collagen turnover in the heart. Therefore, understanding MIF could lead to the identification of biomarkers and targets for prevention and treatment of heart failure in chronic kidney disease patients.

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