期刊
FRONTIERS IN MEDICINE
卷 8, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fmed.2021.615417
关键词
CircHIPK3; miRNA; fibrosis; cancer; pathophysiological; treatment
资金
- National Natural Science Fund [81671003]
circHIPK3 plays an important role in the pathophysiological processes of various diseases, regulating cell proliferation, differentiation, and migration through the action of sponge miRNA. This review explores the specific functional role of circHIPK3 in fibrotic diseases, cancer, and other diseases, aiming to clarify its role in disease processes and provide new ideas for treatments and further studies.
A large number of studies in China and other countries have confirmed that circularHIPK3 (circHIPK3) plays an important role in the pathophysiological processes of various diseases. Through the action of sponge miRNA (miR), circHIPK3 regulates cell proliferation, differentiation, and migration, and plays a key role in disease processes. By referring to a large number of research reports, this article explores the specific functional role of circHIPK3 in fibrotic diseases, cancer, and other diseases. This review aims to clarify the role of circHIPK3 in disease processes in order to aid further studies into the specific pathogenesis and clinical diagnosis of various diseases and provide new ideas for treatments.
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