期刊
ENVIRONMENTAL SCIENCE & TECHNOLOGY
卷 50, 期 7, 页码 4045-4053出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.est.6b00032
关键词
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资金
- Natural Science Foundation of China [21207071, 41225004]
- Fundamental Research Funds for the Central Universities
- US CDC (Atlanta, GA) [1U38EH000464-01]
- US CDC (Atlanta, GA)
In this study, concentrations of bisphenol A (BPA) and seven other bisphenols (BPs) were measured in urine samples collected from people living in and around e-waste dismantling facilities, and in matched reference population from rural and urban areas in China. BPA, :bisphenol S (BPS), and bisphenol F (BPF) were frequently detected (detection frequencies: > 90%) in urine samples collected from individuals who live near e-waste facilities, with geometric mean (GM) concentrations of 2.99 (or 3.75), 0.361 (or 0:469), and 0.349 (or 0.435) ng/mL (or mu g/g Cre), respectively; the other five BPs were rarely found in urine samples, regardless of the sampling location, The urinary concentrations of BPA and BPF, but not BPS, were significantly higher in individuals from e-waste recycling locations than did individuals from a rural reference location. :Our findings, indicated that e-waste dismantling activities contribute to human exposure to BPA and BPF. 8-Hydroxy-2'-deoxyguanosine (8-OHdG) was measured in urine as a marker of oxidative stress. In the e-waste dismantling location, urinary 8-OHdG was significantly and positively correlated (p < 0.001) with urinary BPA and BPS, but not BPF; a similar correlation was also observed in reference sites. These findings suggest that BPA and BPS exposures are associated with elevated oxidative stress.
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